... are specialized astroglial cells, from the external granule layer to the internal granule layer. However, the molecular mechanisms underlying BG development are not well understood. Here, we show that GFAP::Cre;Erbb3 F/F mice, which lack Erbb3 in both radial glia and neurons, exhibit impairments in balance...

... neural crest migration, but also the ability of DRG progenitors to pause at a particular target location where they can receive DRG-promoting signals. In mammalian embryos, a receptor tyrosine kinase proto-oncogene, ErbB3, is required for proper trunk neural crest migration. Here, we show...

... requirements for picasso are not known. Here, we show that picasso is allelic to erbb3b , which encodes an epidermal growth factor receptor (EGFR)-like tyrosine kinase. erbb3b is one of two zebrafish orthologues of human epidermal growth factor receptor 3 ( HER3, ERBB3 ) and part of a larger family...

...Sharon L. Erickson; K. Sue O’Shea; Nazli Ghaboosi; Linda Loverro; Gretchen Frantz; Michelle Bauer; Lucy H. Lu; Mark W. Moore ABSTRACT Heregulins bind directly to ErbB3 and ErbB4 receptors, leading to multiple dimerization possibilities including heterodimerization with the ErbB2 receptor. We have...