... Cytokinesis Epithelial junctions Epithelium Ligue Contre le Cancer http://dx.doi.org/10.13039/501100004099 Fondation ARC pour la Recherche sur le Cancer http://dx.doi.org/10.13039/501100004097 PJA 20191209388 Association Nationale de la Recherche et de la Technologie...

... in the control of lung morphogenesis. These findings are relevant to lung tumorigenesis, in which a pathological function of Nolz1 is implicated. Hematoxylin and eosin (H&E) stains showed that the mesenchyme and epithelium appeared to be similar between wild-type and KO lungs at E12.5 ( Fig. 2 C). By E14.5...

... exerts a function there. As previously reported in the wing imaginal disc epithelium ( Pannen et al., 2020 ), in the pupal notum, depletion of Shrub results in defective localization of SJ components, namely Claudins (Kune-Kune and Sinuous) ( Fig. 5 A; Fig. S5C ), suggesting that Shrub is also required...

.... Summary: Zasp52 is a key component of supracellular actomyosin cables during epithelial morphogenesis that serve to insulate morphogenetic changes from each other. Actomyosin Supracellular cable Junctions Cytoskeleton Tension Epithelium Morphogenesis Medical Research Council http...

... elongation. Development Drosophila Wing Cell junctions Epithelium Exocyst Marie Curie IEF2008 number 237404 Cancer Research UK http://dx.doi.org/10.13039/501100000289 FC001175 Medical Research Council FC001175 Wellcome Trust http://dx.doi.org...

... tissues ( Ehf −/− ) or specifically in the gut epithelium. Ehf −/− mice were born at the expected Mendelian ratio, but showed reduced body weight gain, and developed a series of pathologies requiring most Ehf −/− mice to reach an ethical endpoint before reaching 1 year of age. These included papillomas...

... transcription factors as upstream regulators of Wnt5a in the 4V ChP epithelium. Competing interests The authors declare no competing or financial interests. 23 4 2020 14 4 2021 © 2021. Published by The Company of Biologists Ltd 2021 Summary: MEIS1 regulates WNT5A...

... markers associated with EMT. EMT MET Cancer metastasis Developmental models Epithelium Mesenchyme Epithelial-mesenchymal transition (EMT) and its reverse process mesenchymal-epithelial transition (MET) are dynamic processes – collectively referred to as EMTs – that are associated...

... of the head. In the eye and ear, these neural crest cells then transform back into an epithelium, via mesenchymal-to-epithelial transition (MET), highlighting the flexibility of this population. Elsewhere in the head, the epithelium loses its integrity and transforms into mesenchyme. Here, we review...

... development: orchestrating the generation and regeneration of a complex organ . Development   141 , 502 - 513 . 10.1242/dev.098186 Hogmalm , A. , Bry , M. , Strandvik , B. and Bry , K. ( 2014 ). IL-1β expression in the distal lung epithelium disrupts lung morphogenesis...

... in Drosophila larvae. Wound repair Adherens junctions Epithelium Casein kinase 1α β-Catenin Drosophila Drosophila studies in wound repair and regeneration have provided many insights at the molecular and cellular levels ( Nakamura et al., 2018 ; Tsai et al., 2018 ; Zulueta-Coarasa...

... by The Company of Biologists Ltd 2018 Summary: Dynamic regulation of stem cell fate is required for tissue homeostasis and repair. The stem cell niche integrates local and systemic signals to adjust stem cell behavior to changing needs of the tissue. Epithelium Intestine Lung Niche Skin Stem...

... at parasegmental boundaries, and suppresses epithelial folding along these boundaries, where Hedgehog signalling has opposing effects. Apico-basal polarity Contractility Embryo Epithelium Morphogenesis Planar polarity Biotechnology and Biological Sciences Research Council 10.13039/501100000268...

... the equator. To elucidate the mechanisms underlying lens epithelial cell movement, we conducted time-lapse imaging of zebrafish lens epithelium. Lens epithelial cells do not intermingle but maintain their relative positions during development. Cell division induces epithelial rearrangement, which subsequently...

...Katsumi Fumoto; Hisako Takigawa-Imamura; Kenta Sumiyama; Tomoyuki Kaneiwa; Akira Kikuchi In lung development, the apically constricted columnar epithelium forms numerous buds during the pseudoglandular stage. Subsequently, these epithelial cells change shape into the flat or cuboidal pneumocytes...

... by severe ciliopathies, such as Meckel syndrome, present several ocular surface disease conditions of unclear pathogenesis. Here, we show that primary cilia are predominantly present on basal cells of the mouse corneal epithelium (CE) throughout development and in the adult. Conditional ablation of cilia...

... BMP-Smad1/5 signaling and associated endothelial cells are required for reorganization of the thyroid progenitor cell mass into mature follicles via the assembly of a basement membrane. Thyroid Smad1 Smad5 Follicle Epithelium Extracellular matrix Mouse Thyroid follicles...

... in epithelia. We have studied the role of spectrins during epithelia morphogenesis using the Drosophila follicular epithelium (FE). As previously described, we show that α-Spectrin and β-Spectrin are essential to maintain a monolayered FE, but, contrary to previous work, spectrins are not required to control...

.... Inductive interactions between epithelium and mesenchyme regulate gut development, but the influence of these interactions on ENS development is unknown. Epithelial-mesenchymal recombinations were constructed using avian hindgut mesenchyme and non-intestinal epithelium from the bursa of Fabricius...

... understood. The embryonic pancreas, which gives rise to β-cells, undergoes early epithelial rearrangements, including transient stratification of an initially monolayered epithelium, followed by microlumen formation and later resolution into branches. Within the epithelium, a multipotent progenitor cell (MPC...