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Keywords: Epithelium
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Journal Articles
Journal: Development
Development (2021) 148 (20): dev199731.
Published: 14 October 2021
... , F. and Eaton , S. ( 2010 ). Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila . Cell 142 , 773 - 786 . 10.1016/j.cell.2010.07.042 Bai , J. , Chiu , W. , Wang , J. , Tzeng , T. , Perrimon , N. and Hsu , J. ( 2001...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (12): dev199542.
Published: 28 June 2021
... tissues ( Ehf −/− ) or specifically in the gut epithelium. Ehf −/− mice were born at the expected Mendelian ratio, but showed reduced body weight gain, and developed a series of pathologies requiring most Ehf −/− mice to reach an ethical endpoint before reaching 1 year of age. These included papillomas...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (10): dev192054.
Published: 25 May 2021
... transcription factors as upstream regulators of Wnt5a in the 4V ChP epithelium. Despite large overlap in their cellular architecture and secretory capacity, ChPs adopt dramatically different morphologies during development. Here, we report a novel role for epithelium-derived WNT5A in the regulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (8): dev198036.
Published: 20 April 2021
... markers associated with EMT. EMT MET Cancer metastasis Developmental models Epithelium Mesenchyme Epithelial-mesenchymal transition (EMT) and its reverse process mesenchymal-epithelial transition (MET) are dynamic processes – collectively referred to as EMTs – that are associated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (4): dev196030.
Published: 15 February 2021
... of the head. In the eye and ear, these neural crest cells then transform back into an epithelium, via mesenchymal-to-epithelial transition (MET), highlighting the flexibility of this population. Elsewhere in the head, the epithelium loses its integrity and transforms into mesenchyme. Here, we review...
Journal Articles
Journal: Development
Development (2020) 147 (4): dev181560.
Published: 20 February 2020
.../ Highlighted Article: Loss of Cyp26b1 results in neonatal lethality due to failure of distal lung epithelial differentiation, with increased AT2 and decreased AT1 cell types. Lung Cyp26b1 Epithelium Retinoic acid Endothelial cell Epithelial cell Mouse Organogenesis requires tightly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (20): dev175133.
Published: 02 October 2019
... and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing . Nat. Commun.   7 , 12972 . 10.1038/ncomms12972 Larue , L. , Ohsugi , M. , Hirchenhain , J. and Kemler , R. ( 1994 ). E-cadherin null mutant embryos fail to form a trophectoderm epithelium...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (15): dev165399.
Published: 01 August 2018
.... Epithelium Intestine Lung Niche Skin Stem cells Epithelial tissues such as the lung, gastrointestinal tract and skin undergo continuous cell replacement in a process termed homeostasis ( Blanpain and Fuchs, 2014 ; Leeman et al., 2014 ). This process depends on the dynamic activity of tissue...
Journal Articles
Journal: Development
Development (2018) 145 (8): dev155325.
Published: 24 April 2018
... at parasegmental boundaries, and suppresses epithelial folding along these boundaries, where Hedgehog signalling has opposing effects. Apico-basal polarity Contractility Embryo Epithelium Morphogenesis Planar polarity Epithelial sheet bending is essential to elaborate the anatomy of animal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (4): 708–719.
Published: 15 February 2017
... the equator. To elucidate the mechanisms underlying lens epithelial cell movement, we conducted time-lapse imaging of zebrafish lens epithelium. Lens epithelial cells do not intermingle but maintain their relative positions during development. Cell division induces epithelial rearrangement, which subsequently...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (1): 151–162.
Published: 01 January 2017
...Katsumi Fumoto; Hisako Takigawa-Imamura; Kenta Sumiyama; Tomoyuki Kaneiwa; Akira Kikuchi In lung development, the apically constricted columnar epithelium forms numerous buds during the pseudoglandular stage. Subsequently, these epithelial cells change shape into the flat or cuboidal pneumocytes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (12): 2160–2171.
Published: 15 June 2016
... by severe ciliopathies, such as Meckel syndrome, present several ocular surface disease conditions of unclear pathogenesis. Here, we show that primary cilia are predominantly present on basal cells of the mouse corneal epithelium (CE) throughout development and in the adult. Conditional ablation of cilia...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (11): 1958–1970.
Published: 01 June 2016
... for reorganization of the thyroid progenitor cell mass into mature follicles via the assembly of a basement membrane. Thyroid Smad1 Smad5 Follicle Epithelium Extracellular matrix Mouse Thyroid follicles are the functional units of the thyroid gland. Each follicle is composed of a polarized...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (8): 1388–1399.
Published: 15 April 2016
... in epithelia. We have studied the role of spectrins during epithelia morphogenesis using the Drosophila follicular epithelium (FE). As previously described, we show that α-Spectrin and β-Spectrin are essential to maintain a monolayered FE, but, contrary to previous work, spectrins are not required to control...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (2): 264–275.
Published: 15 January 2016
.... Inductive interactions between epithelium and mesenchyme regulate gut development, but the influence of these interactions on ENS development is unknown. Epithelial-mesenchymal recombinations were constructed using avian hindgut mesenchyme and non-intestinal epithelium from the bursa of Fabricius...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (1): 101–112.
Published: 01 January 2016
... understood. The embryonic pancreas, which gives rise to β-cells, undergoes early epithelial rearrangements, including transient stratification of an initially monolayered epithelium, followed by microlumen formation and later resolution into branches. Within the epithelium, a multipotent progenitor cell (MPC...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (22): 3954–3963.
Published: 15 November 2015
..., root-forming cervical loops and enamel-forming ameloblasts. Enamel knots are signaling centers that define the positions of cusp tips in a tooth by instructing the adjacent epithelium to fold and proliferate. Here, we show that the forkhead-box transcription factor Foxi3 inhibits formation of enamel...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (20): 4006–4017.
Published: 15 October 2014
... and Wieschaus, 1996 ). From this, we inferred the position along the apico-basal axis of all membranous/cortical lines with comparable localisations ( supplementary material Table S4 ). The epithelium of stage 5-10 embryos is still polarizing and the junctional and membranous domains are immature compared...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (23): 4740–4750.
Published: 01 December 2013
... epithelium is a landmark-rich tissue, marked by regularly spaced ridges (rugae), making it an excellent model in which to analyse the contributions of cellular processes to directional tissue growth. We captured confocal stacks of entire fixed mouse palate epithelia throughout the mid-gestation growth period...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (9): 2015–2026.
Published: 01 May 2013
... molecular evidence that the human thymic epithelium derives solely from the third pharyngeal pouch, as in the mouse, in contrast to previous suggestions. Finally, we define the timing of onset of hematopoietic cell colonization and epithelial cell differentiation in the human thymic primordium, showing...
Includes: Supplementary data