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Keywords: Epithelial-to-mesenchymal transition
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Neural development
Journal: Development
Development (2022) 149 (15): dev200068.
Published: 8 August 2022
... vesicles at the apical surface and interacts with β/δ-catenins during neural tube closure, and Irf6 is involved in defining neural fold borders by restricting AP2α expression. Twist1 suppresses Irf6 and other epithelial genes in CNCCs during the epithelial-to-mesenchymal transition (EMT) process and cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (15): dev200331.
Published: 29 July 2022
.../10.13039/501100003447 European Social Fund http://dx.doi.org/10.13039/501100004895 MIS 5033021 Embryo Epithelial-to-mesenchymal transition Neural crest Neuroblastoma Summary: In this Review, we focus on recent studies describing mouse and human neural crest-derived...
Journal Articles
Journal: Development
Development (2016) 143 (7): 1192–1204.
Published: 1 April 2016
... in Grhl2 mutants. Our in vitro assays show that they act as suppressors of the epithelial-to-mesenchymal transition (EMT). Thus, GRHL2 promotes the epithelial nature of the NNE during the dynamic events of neural tube formation by both activating key epithelial genes and actively suppressing EMT through...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (21): 3630–3636.
Published: 1 November 2015
... of the epithelialmesenchymal transition and its effects on embryonic stem cells . Exp. Mol. Med.   46 , e108 . 10.1038/emm.2014.44 Lindsay , S. and Copp , A. J. ( 2005 ). MRC–Wellcome Trust Human Developmental Biology Resource: enabling studies of human developmental gene expression . Trends...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (12): 2139–2149.
Published: 15 June 2012
... tracing using a tamoxifen-inducible Cre expressed from the Tcf21 locus demonstrated that the majority of Tcf21-expressing epicardial cells are committed to the cardiac fibroblast lineage prior to initiation of epicardial epithelial-to-mesenchymal transition (EMT). Furthermore, Tcf21 null hearts fail...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (12): 2359–2369.
Published: 15 June 2006
... regression in organ culture. Müllerian duct regression can also be inhibited or accelerated by siRNA targeting Smad8 and Smad5 ,respectively. Thus, the early action of MIS is to initiate an epithelial-to-mesenchymal transition of MISRII-expressing cells and to specify the components of the receptor/SMAD...