... signalling. There is also no evidence for actin-rich filopodia at the bud tips. Rather, we find epithelial tubes to be collapsed during early lung and kidney development, and we observe fluid flow in the narrow tubes. By simulating the measured fluid flow inside segmented narrow epithelial tubes, we show...

... Epithelial tube Morphogenesis Neural tube Zebrafish Epithelia are one of the fundamental tissue types of the body, forming protective sheets of cells around the outside of the organism and lining the inside surface of many organs or parts of organs. All epithelia are polarised and have an apical...

..., the mechanisms underpinning the cellular mechano-response system that maintains size along an axis of a polarized tissue remain elusive. Here, we show how the diameter of an epithelial tube is maintained during murine epididymal development by combining quantitative imaging, mechanical perturbation...

... , A. , et al. ( 2015 ). MorphoGraphX: a platform for quantifying morphogenesis in 4D . Elife   4 , 05864 . 10.7554/eLife.05864 Beitel , G. J. and Krasnow , M. A. ( 2000 ). Genetic control of epithelial tube size in the Drosophila tracheal system . Development   127 , 3271 - 3282...

... 6 2006 © 2006. 2006 Echinoid Epithelial morphogenesis Actomyosin cable Follicular epithelium Dorsal closure Epithelial tube The morphogenesis of diverse epithelia during development derives from coordinated remodeling of cell shape and intercellular interactions that drives...

...Greg J. Beitel; Mark A. Krasnow ABSTRACT The proper size of epithelial tubes is critical for the function of the lung, kidney, vascular system and other organs, but the genetic and cellular mechanisms that control epithelial tube size are unknown. We investigated tube size control in the embryonic...