... OFT development by conditionally deleting both Bmp4 and Bmp7 in the second heart field (SHF). SHF Bmp4/7 deficiency resulted in defective epithelial to mesenchymal transition (EMT) and reduced cardiac neural crest ingress, with resultant persistent truncus arteriosus. Using a candidate gene approach...

... ). Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development . Mech. Dev. 120 , 1351 – 1383 . Simpson L. , Wieschaus E. ( 1990 ). Zygotic activity of the nullo locus is required to stabilize the actin-myosin network during cellularization in Drosophila...

...Irit Shoval; Andreas Ludwig; Chaya Kalcheim During neural crest ontogeny, an epithelial to mesenchymal transition is necessary for cell emigration from the dorsal neural tube. This process is likely to involve a network of gene activities, which remain largely unexplored. We demonstrate that N...

... Epithelial to mesenchymal transition Muscle Myod Myf5 Pax3 Pax7 Somite The embryonic myotome is the source of all epaxial and hypaxial skeletal muscles. The mechanisms underlying myotome development were recently reevaluated ( Brent and Tabin,2002 ; Buckingham,2001 ; Hollway...

... Avian embryo Cell cycle Cyclin D1 Epithelial to mesenchymal transition Neural tube Somite The neural crest (NC) is a unique population of embryonic progenitors that generates a rich variety of derivatives( Le Douarin and Kalcheim,1999 ; Kalcheim,2000 ; Knecht and Bronner-Fraser, 2002...