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Keywords: Epithelial self-renewal
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Journal Articles
Cristina Brischetto, Karsten Krieger, Christian Klotz, Inge Krahn, Séverine Kunz, Marina Kolesnichenko, Patrick Mucka, Julian Heuberger, Claus Scheidereit, Ruth Schmidt-Ullrich
Journal:
Development
Development (2021) 148 (21): dev199683.
Published: 9 November 2021
... stem cells of small intestinal (SI) crypts. To examine NF–κB functions in SI epithelial self-renewal, mice or SI crypt organoids (‘mini-guts’) with ubiquitously suppressed NF-κB activity were used. We show that NF-κB activity is dispensable for maintaining SI epithelial proliferation, but is essential...
Includes: Supplementary data
