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Keywords: Epithelial polarity
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Journal Articles
Journal: Development
Development (2022) 149 (3): dev200110.
Published: 3 February 2022
... remain difficult to tease apart. Atf3 has recently been shown to control the expression of genes involved in the maintenance of epithelial polarity, and to be specifically activated in polarity-deficient cells and required in the RasV12/scrib − overgrowth model ( Atkins et al., 2016 ; Donohoe et al...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (19): dev199513.
Published: 5 October 2021
... of the mouse Huntington's disease gene homolog Hdh . Science 269 , 407 - 410 . 10.1126/science.7618107 Elias , S. , Mcguire , J. R. , Yu , H. and Humbert , S. ( 2015 ). Huntingtin is required for epithelial polarity through RAB11A-mediated apical trafficking of PAR3-aPKC...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (15): dev175497.
Published: 12 August 2019
... confers apical identity, Par-complex assembly and Crb accumulation to promote epithelial morphogenesis. Epithelial polarity Cdc42 Par6 Par3 Bazooka aPKC Crumbs Par complex Epithelial cell polarity and morphogenesis involve the specification and maturation of distinct plasma membrane...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (2): dev157909.
Published: 26 January 2018
... by the basolateral PDZ protein Scribble . Nature   403 , 676 - 680 . 10.1038/35001108 Bilder , D. , Schober , M. and Perrimon , N. ( 2003 ). Integrated activity of PDZ protein complexes regulates epithelial polarity . Nat. Cell Biol.   5 , 53 - 58 . 10.1038/ncb897 Bischof , J...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1684–1694.
Published: 1 May 2015
.../ncb2508 Xiong , X. , Xu , Q. , Huang , Y. , Singh , R. D. , Anderson , R. , Leof , E. , Hu , J. and Ling , K. ( 2012 ). An association between type Igamma PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization . Mol. Biol. Cell   23...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (7): 1305–1314.
Published: 1 April 2015
...Joaquim Grego-Bessa; Jeffrey Hildebrand; Kathryn V. Anderson The genetic control of mammalian epithelial polarity and dynamics can be studied in vivo at cellular resolution during morphogenesis of the mouse neural tube. The mouse neural plate is a simple epithelium that is transformed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (13): 2787–2797.
Published: 1 July 2013
... ), similar to the gradual Par3 localization during zebrafish development ( Tawk et al., 2007 ). Therefore ArhGEf18 becomes apically enriched alongside known regulators of a-b polarity, in line with a function of ArhGEF18 in epithelial polarity. Author contributions The mutations were cloned by F.L...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (11): 2061–2070.
Published: 1 June 2012
... adaptor AP-1 in the C. elegans intestine, we found that AP-1 is required for epithelial polarity maintenance. Depletion of AP-1 subunits does not affect epithelial polarity establishment or the formation of the intestinal lumen. However, the loss of AP-1 affects the polarised distribution of both apical...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (11): 2050–2060.
Published: 1 June 2012
... polarize around a central lumen, provides a simple system with which to understand the coordination of epithelial polarity. We show that cell fate regulators cause pharyngeal precursor cells to group into a bilaterally symmetric, rectangular array of cells called the double plate. The double plate cells...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (9): 2057–2067.
Published: 1 May 2005
... (e-mail: sive@wi.mit.edu ) 15 2 2005 ©2005. 2005 Brain ventricle formation Brain structure Circulation Morphogenesis Zebrafish Lumen inflation snakehead ( snk ) nagie oko ( nok ) Neural tube Epithelial polarity MAGUK family Na + K + ATPase atp1a1a.1...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 977–986.
Published: 1 March 2005
... the opposite effect of expanding the basolateral domain ( Fig. 4K ). Localisation of basolateral markers all around the cell membrane is a distinctive feature of inner apolar cells. Therefore, we conclude that the epithelial polarity of the cells is lost and that they now resemble, in their membrane...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 1939–1948.
Published: 1 May 2004
... pathway. Clones for null alleles of Pvr or expression of RNAi constructs showed no phenotypes in the wing disc or pupal wing, suggesting that Pvr plays a redundant role in this tissue. However, when uniform expression of a constitutively dimerizing receptor was induced, loss of epithelial polarity...
Journal Articles
Journal: Development
Development (2003) 130 (12): 2657–2668.
Published: 15 June 2003
... Epithelial polarity Occludin The late blastula Xenopus embryo is shielded from the exterior by one layer of superficial cells that provide a tight-junction mediated epithelial seal. Underneath this superficial layer, there are several layers of non-epithelial deep cells ( Hausen and Riebesell...
Includes: Multimedia, Supplementary data