...: An smFISH-based survey identifies a subset of mRNAs encoding junctional components that localize at or in proximity to the adherens junction through a translation-dependent mechanism. dlg-1 Apical junctions Epithelial morphogenesis mRNA localization Schweizerischer Nationalfonds zur...

... ), and studies in vertebrates have described the role of the BM in TGFβ activity ( Saika et al., 2001 ). Thus, measuring local BM mechanical properties from stage 2 to stage 10 should provide valuable information to help decipher the link between BM and epithelial morphogenesis. To investigate this link, we...

... competes with the Notch ligand Delta as a substrate for Mib1 E3 ligase to coordinate neuronal specification and differentiation at the post-translational level. Notch signaling Mind bomb Zebrafish Epb41l5 Neurogenesis Neuronal differentiation Epithelial morphogenesis Neural progenitor...

...Thorsten Horn; Kristen A. Panfilio Epithelial morphogenesis, the progressive restructuring of tissue sheets, is fundamental to embryogenesis. In insects, not only embryonic tissues but also extraembryonic (EE) epithelia play a crucial role in shaping the embryo. In Drosophila , the T-box...

... significantly between drosophilid species. Epithelial morphogenesis Tube formation Evolution Drosophila Scaptodrosophila The extent of morphological diversity across the animal kingdom is extremely large, but our current understanding of how this diversity arises is limited ( Mallarino...

... embryogenesis. Girdin GIV Epithelial tissues Epithelial morphogenesis Cell-cell adhesion E-cadherin Armadillo Drosophila melanogaster Cell motility plays a fundamental role during animal development and is essential for tissue homeostasis ( Friedl and Gilmour, 2009 ). The cytoskeletal...

... of placental development and epithelial morphogenesis. These genes included that encoding the serine protease inhibitor Kunitz type 1 ( Spint1 ), which regulates BCT cell integrity and labyrinth formation. In human placenta, we found that human orthologs of murine GRHL2 and its targets displayed co-regulation...

.... 109 , 91 - 94 . 10.1016/0040-8166(88)90015-8 Fristrom , D. ( 1988 ). The cellular basis of epithelial morphogenesis . Tissue Cell 20 , 645 - 690 . Gibbons , I. R. ( 1961 ). The relationship between the fine structure and direction of beat in gill cilia of a lamellibranch...

... provided that the original work is properly attributed. Epithelial morphogenesis Fgf8 Pharyngeal pouches Tbx1 Wnt11r Zebrafish From the embryonic endoderm emerge a number of epithelial outpocketings that generate the initial anlagen of diverse organs. In the head, these include a series...

... The authors declare no competing financial interests. 12 12 2013 15 5 2014 © 2014. Published by The Company of Biologists Ltd 2014 Epithelial morphogenesis Junctional dynamics Mechanical forces Quantitative image analysis Segmentation algorithms Wound healing Drosophila...

... tracheal systems . Development 133 , 785 – 790 . Fristrom D. ( 1988 ). The cellular basis of epithelial morphogenesis. A review . Tissue Cell 20 , 645 – 690 . Fritzenwanker J. H. , Technau U. ( 2002 ). Induction of gametogenesis in the basal cnidarian Nematostella...

... of Stard13 expression in the pancreas disrupts epithelial morphogenesis and tip-domain organisation, resulting in hampered proliferation of tip progenitors and subsequent organ hypoplasia. Stard13 acts by regulating Rho signalling spatially and temporally during pancreas development. Our findings provide new...

...Dandan Chu; Hanshuang Pan; Ping Wan; Jing Wu; Jun Luo; Hong Zhu; Jiong Chen During epithelial morphogenesis, cells not only maintain tight adhesion for epithelial integrity but also allow dynamic intercellular movement to take place within cell sheets. How these seemingly opposing processes...

..., consistent with a role for Rhou in regulating JNK activity. Downregulation of Rhou in individual endoderm cells results in a reduced ability of these cells to occupy the apical territory of the epithelium. Our findings highlight epithelial morphogenesis as a required intermediate step in the differentiation...

.... , Brown N. H. ( 2004 ). Novel functions for integrins in epithelial morphogenesis . Curr. Biol. 14 , 381 - 385 . Narasimha M. , Brown N. H. ( 2006 ). Confocal microscopy of Drosophila embryos . In Cell Biology: A Laboratory Handbook , Vol. 3 (ed. Celis J. E. ), pp...

... of neuronal migration in the vertebrate brain, might be a component of this signaling pathway, but this idea has been controversial. We now demonstrate that null mutations of Drosophila Dab result in phenotypes that mimic Abl mutant phenotypes, both in axon guidance and epithelial morphogenesis. The Dab...

... transcriptional target of JNK signalling and reveal the first secreted regulator of the JNK pathway acting in a negative-feedback loop during epithelial morphogenesis. References Abbott M. K. , Lengyel J. A. ( 1991 ). Embryonic head involution and rotation of male terminalia require...

... ( nharden@sfu.ca ) Competing interests statement The authors declare no competing financial interests. 20 4 2010 © 2010. 2010 Drosophila Pak Scribble Apicobasal polarity Dorsal closure Epithelial morphogenesis Epithelial cells are typically polarized...

... of these functions have not been verified in genetically tractable systems. Using an established follicular epithelial model in Drosophila , we show that the Drosophila VHL gene is involved in epithelial morphogenesis via stabilizing microtubule bundles and aPKC. Microtubule defects in VHL mutants lead...

... in Drosophila ovarian follicle cells . Dev. Dyn. 218 , 80 - 93 . Dorman J. B. , James K. E. , Fraser S. E. , Kiehart D. P. , Berg C. A. ( 2004 ). bullwinkle is required for epithelial morphogenesis during Drosophila oogenesis . Dev. Biol. 267 , 320 - 341...