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Keywords: Epithelia
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Journal Articles
Journal: Development
Development dev.202420.
Published: 1 February 2024
... lethality, partial tissue fusion rescue, and restoration of tissue form within the craniofacial epithelia. These data suggest that aberrant epithelial maintenance, partially regulated by Noggin -mediated regulation of BMP-Smad pathways, may underpin tissue fusion defects in Grhl2 −/- mice. * Authors...
Journal Articles
Journal: Development
Development (2023) 150 (13): dev201747.
Published: 30 June 2023
... of cell extrusion/cell death events in large movies of epithelia marked with cell contour. The pipeline, initially trained on movies of the Drosophila pupal notum marked with fluorescent E-cadherin, is easily trainable, provides fast and accurate extrusion predictions in a large range of imaging...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (10): dev197301.
Published: 17 May 2021
... typically powered by the contractile actomyosin cytoskeleton. This has been investigated mainly in homogeneous epithelia, where intercalation takes minutes. However, in some tissues, intercalation involves different cell types and can take hours. Whether slow and fast intercalation share the same mechanisms...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev192773.
Published: 12 March 2021
... Summary: This Primer explains and provides advice on two- and three-dimensional stress inference, an increasingly popular technique to identify the role of mechanics during embryo development. Mechanical stress inference Cell junction tension Cell pressure Cell shape Epithelia Development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194589.
Published: 23 December 2020
...Benoit Aigouy; Claudio Cortes; Shanda Liu; Benjamin Prud'Homme ABSTRACT Epithelia are dynamic tissues that self-remodel during their development. During morphogenesis, the tissue-scale organization of epithelia is obtained through a sum of individual contributions of the cells constituting...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (4): dev169037.
Published: 15 February 2019
... was successfully accomplished in both genotypes; however, apical sides of the initial wounded sites in Dronc-RNAi and Duox-RNAi flies showed autofluorescence cell remnants ( Fig. S7B,C ). These remnants could be attributed to cellular debris of wounded epithelia and/or immune cells. As the debris was completely...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (2): dev157941.
Published: 26 January 2018
.... , Nakanishi , H. , Miyoshi , J. , Mandai , K. , Ishizaki , H. , Tanaka , M. , Togawa , A. , Takahashi , K. , Nishioka , H. , Yoshida , H. , et al. ( 1999 ). Afadin: a key molecule essential for structural organization of cell-cell junctions of polarized epithelia during...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (13): 2517–2528.
Published: 1 July 2017
... Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: Single-cell sequencing combined with a battery of molecular tools reveals novel features of cellular dynamics and differentiation during lacrimal gland development in mice. Lacrimal gland Epithelia Single cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (10): 1876–1886.
Published: 15 May 2017
... of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: A combination of experimental work and theory reveals how gradients in transcription, signaling and resulting contractility shape tissue folding. Epithelia Fold Gradient Myosin Twist Actomyosin-associated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (9): 1725–1734.
Published: 1 May 2017
... species. Image segmentation Cell tracking Planar polarity Epithelia Morphogenesis Convergent extension Drosophila Changes in epithelial organization are essential for tissue development, regeneration and repair. Advances in microscopy have made it possible to visualize dynamic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (14): 2573–2581.
Published: 15 July 2016
... is not required in the wing disc because there are parallel mechanisms for Mud localization and hence spindle orientation, making it a more robust system than in other epithelia. References Basto , R. , Brunk , K. , Vinadogrova , T. , Peel , N. , Franz , A. , Khodjakov...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (17): 3046–3057.
Published: 1 September 2015
...Myrto Deligiannaki; Abbie L. Casper; Christophe Jung; Ulrike Gaul Epithelial sheets play essential roles as selective barriers insulating the body from the environment and establishing distinct chemical compartments within it. In invertebrate epithelia, septate junctions (SJs) consist of large...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 282–290.
Published: 15 January 2015
... show that loss of Cα, the predominant C-terminal p63 variant in epithelia, promotes the transcriptional activity of TAp63 and also impairs the dominant-negative activity of ΔNp63, thereby controlling p21 Waf1/Cip1 expression. We propose that the p63 C-terminus links cell cycle control...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4279–4284.
Published: 15 November 2014
... transitions have focused on the cell-autonomous changes, while less is known about the role of neighboring epithelial cells in facilitating such transitions. Caenorhabditis elegans EMT Delamination Epithelia Junction Ras © 2014. Published by The Company of Biologists Ltd 2014 29 4...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 2978–2983.
Published: 1 August 2014
...Lara C. Skwarek; Sarah L. Windler; Geert de Vreede; Gregory C. Rogers; David Bilder The Par-3/Par-6/aPKC complex is the primary determinant of apical polarity in epithelia across animal species, but how the activity of this complex is restricted to allow polarization of the basolateral domain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (14): 2796–2802.
Published: 15 July 2014
... no competing financial interests. 11 11 2013 13 5 2014 © 2014. Published by The Company of Biologists Ltd 2014 Drosophila Endocytosis Epithelia Polarity Retromer The polarized distribution of proteins is central to biological function. Foundational work has identified...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2013) 140 (14): 2851–2855.
Published: 15 July 2013
...@mcdb.ucla.edu ; beitel@northwestern.edu ) Competing interests statement The authors declare no competing financial interests. © 2013. Published by The Company of Biologists Ltd 2013 Tubulogenesis Endothelia Epithelia Morphogenesis Lumen Tubes are the fundamental...
Journal Articles
Journal: Development
Development (2013) 140 (1): 13–21.
Published: 1 January 2013
..., it is still unclear how adherens junctions are positioned at the interface of apical and basolateral domains in epithelia. Combining computational models with experiments has led to great progress in understanding cell polarity in yeast budding, the worm zygote and fly follicular epithelium. Other cell...
Journal Articles