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Keywords: Epithelia
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Journal Articles
Journal: Development
Development (2021) 148 (10): dev197301.
Published: 17 May 2021
... typically powered by the contractile actomyosin cytoskeleton. This has been investigated mainly in homogeneous epithelia, where intercalation takes minutes. However, in some tissues, intercalation involves different cell types and can take hours. Whether slow and fast intercalation share the same mechanisms...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev192773.
Published: 12 March 2021
...-dimensional stress inference, an increasingly popular technique to identify the role of mechanics during embryo development. Mechanical stress inference Cell junction tension Cell pressure Cell shape Epithelia Development The roles of mechanical interactions during morphogenesis, proposed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194589.
Published: 23 December 2020
...Benoit Aigouy; Claudio Cortes; Shanda Liu; Benjamin Prud'Homme ABSTRACT Epithelia are dynamic tissues that self-remodel during their development. During morphogenesis, the tissue-scale organization of epithelia is obtained through a sum of individual contributions of the cells constituting...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (4): dev169037.
Published: 15 February 2019
... and until the termination of thorax closure ( Fig. 1 B-D, Fig. S1 ). Although the entire notum epithelia were composed of cells with previously activated caspase 3 (GFP + cells), scattered RFP + cells were specifically detected at the leading edge. Given that CasT labeling depends on the Gal4/UAS system...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (2): dev157941.
Published: 26 January 2018
... cue for setting up the apical-basal polarity axis, is regulated by active Rap1 acting both through, and independently of, the Cno Rap1-binding domain. Cadherin Cell adhesion Morphogenesis Epithelia Polarity Canoe/Afadin, Drosophila Cell polarity – the ability to differentially...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (13): 2517–2528.
Published: 1 July 2017
... Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: Single-cell sequencing combined with a battery of molecular tools reveals novel features of cellular dynamics and differentiation during lacrimal gland development in mice. Lacrimal gland Epithelia Single cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (10): 1876–1886.
Published: 15 May 2017
... is uniform. Our data argue that apical contractility gradients are important for tissue folding. Epithelia Fold Gradient Myosin Twist Actomyosin-associated folding of epithelial sheets is a common mode of morphogenesis during the development of complex organs and organisms. Defects...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (9): 1725–1734.
Published: 1 May 2017
... epithelial remodeling in various species. Image segmentation Cell tracking Planar polarity Epithelia Morphogenesis Convergent extension Drosophila Changes in epithelial organization are essential for tissue development, regeneration and repair. Advances in microscopy have made...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (14): 2573–2581.
Published: 15 July 2016
... is not required in the wing disc because there are parallel mechanisms for Mud localization and hence spindle orientation, making it a more robust system than in other epithelia. * Present address: Department of Biology, University of Rochester, Rochester, NY 14627, USA. ‡ Present address: Faculty...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (17): 3046–3057.
Published: 1 September 2015
...Myrto Deligiannaki; Abbie L. Casper; Christophe Jung; Ulrike Gaul Epithelial sheets play essential roles as selective barriers insulating the body from the environment and establishing distinct chemical compartments within it. In invertebrate epithelia, septate junctions (SJs) consist of large...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 282–290.
Published: 15 January 2015
... show that loss of Cα, the predominant C-terminal p63 variant in epithelia, promotes the transcriptional activity of TAp63 and also impairs the dominant-negative activity of ΔNp63, thereby controlling p21 Waf1/Cip1 expression. We propose that the p63 C-terminus links cell cycle control...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4279–4284.
Published: 15 November 2014
...@mail.med.upenn.edu ) Competing interests The authors declare no competing financial interests. 29 4 2014 5 9 2014 © 2014. Published by The Company of Biologists Ltd 2014 Caenorhabditis elegans EMT Delamination Epithelia Junction Ras Author contributions J.M.P...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 2978–2983.
Published: 1 August 2014
...Lara C. Skwarek; Sarah L. Windler; Geert de Vreede; Gregory C. Rogers; David Bilder The Par-3/Par-6/aPKC complex is the primary determinant of apical polarity in epithelia across animal species, but how the activity of this complex is restricted to allow polarization of the basolateral domain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (14): 2796–2802.
Published: 15 July 2014
... no competing financial interests. 11 11 2013 13 5 2014 © 2014. Published by The Company of Biologists Ltd 2014 Drosophila Endocytosis Epithelia Polarity Retromer The polarized distribution of proteins is central to biological function. Foundational work has identified...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (4): 889–898.
Published: 15 February 2014
...Sonia Hall; Courtney Bone; Kenzi Oshima; Liang Zhang; Molly McGraw; Bethany Lucas; Richard G. Fehon; Robert E. Ward, IV Polarized epithelia play crucial roles as barriers to the outside environment and enable the formation of specialized compartments for organs to carry out essential functions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (14): 2851–2855.
Published: 15 July 2013
...@mcdb.ucla.edu ; beitel@northwestern.edu ) Competing interests statement The authors declare no competing financial interests. © 2013. Published by The Company of Biologists Ltd 2013 Tubulogenesis Endothelia Epithelia Morphogenesis Lumen Tubes are the fundamental...
Journal Articles
Journal: Development
Development (2013) 140 (1): 13–21.
Published: 1 January 2013
... is a permissive factor for the invasive behavior of discs large tumor cells in Drosophila ovarian follicular epithelia . Development 130 , 1927 – 1935 . Adams A. E. , Johnson D. I. , Longnecker R. M. , Sloat B. F. , Pringle J. R. ( 1990 ). CDC42 and CDC43, two additional genes...
Journal Articles
Journal: Development
Development (2012) 139 (5): 979–990.
Published: 1 March 2012
... of extracellular leucine-rich repeat only (eLRRon) proteins in C. elegans (LET-4 and EGG-6) that are expressed on the apical surfaces of epidermal cells and some tubular epithelia, including the excretory duct and pore. A previously characterized paralog, SYM-1, is also expressed in epidermal cells and secreted...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (10): 1861–1871.
Published: 15 May 2007
... fate determination in the wing, suggesting a broader link between Dpp function and junctional integrity during epithelial development. * Author for correspondence (e-mail: cagan@wustl.edu ) 11 3 2007 © 2007. 2007 Adhesion BMP Dpp Epithelia Patterning Guiding cells...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (5): 999–1009.
Published: 1 March 2007
...@northwestern.edu ) * These authors contributed equally to this work 14 12 2006 © 2007. 2007 MAGUK Cell junction Basolateral Epithelia Drosophila Trachea The function of organs such as the lung, kidney and vascular system depends on epithelial and endothelial tubes...
Includes: Supplementary data