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Keywords: Epithelia
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Journal Articles
Journal: Development
Development dev.197301.
Published: 26 April 2021
... by the contractile actomyosin cytoskeleton. This has mostly been investigated in homogeneous epithelia where intercalation takes minutes. However, in some tissues, intercalation involves different cell types and can take hours. Whether slow and fast intercalation share the same mechanisms remains to...
Journal Articles
Journal: Development
Development (2021) 148 (18): dev192773.
Published: 12 March 2021
... tensile stress is applied to epithelia. This involves the activation of Rho signalling; when that signalling fails, the epithelium fractures. Can stress inference capture the role of mechanical stress in this tissue? This question needs to be subdivided. Are the assumptions for stress inference valid...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194589.
Published: 23 December 2020
...Benoit Aigouy; Claudio Cortes; Shanda Liu; Benjamin Prud'Homme ABSTRACT Epithelia are dynamic tissues that self-remodel during their development. During morphogenesis, the tissue-scale organization of epithelia is obtained through a sum of individual contributions of the cells constituting the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (4): dev169037.
Published: 15 February 2019
... Biologists Ltd 2019 http://www.biologists.com/user-licence-1-1/ Summary:   Drosophila caspase 9 (Dronc), which is spatio-temporally activated in a non-apoptotic context, delays epithelial closure and may be involved in ROS generation. Drosophila Epithelia Live imaging Thorax closure...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (2): dev157941.
Published: 26 January 2018
... Rap1-binding domain. Cadherin Cell adhesion Morphogenesis Epithelia Polarity Canoe/Afadin, Drosophila Cell polarity – the ability to differentially target proteins to distinct plasma membrane domains – is a fundamental cellular property, underlying processes from bacterial motility...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (13): 2517–2528.
Published: 01 July 2017
... and differentiation during lacrimal gland development in mice. Lacrimal gland Epithelia Single cell sequencing Development Tubulogenesis The lacrimal gland secretes tears to provide the aqueous layer of the tear film, which is essential to ocular surface homeostasis. Tears are...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (10): 1876–1886.
Published: 15 May 2017
... The Company of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: A combination of experimental work and theory reveals how gradients in transcription, signaling and resulting contractility shape tissue folding. Epithelia Fold Gradient Myosin Twist...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (9): 1725–1734.
Published: 01 May 2017
... epithelial remodeling in various species. Image segmentation Cell tracking Planar polarity Epithelia Morphogenesis Convergent extension Drosophila Changes in epithelial organization are essential for tissue development, regeneration and repair. Advances in microscopy have made it...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (14): 2573–2581.
Published: 15 July 2016
... not required in the wing disc because there are parallel mechanisms for Mud localization and hence spindle orientation, making it a more robust system than in other epithelia. * Present address: Department of Biology, University of Rochester, Rochester, NY 14627, USA. ‡ Present address...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (17): 3046–3057.
Published: 01 September 2015
...Myrto Deligiannaki; Abbie L. Casper; Christophe Jung; Ulrike Gaul Epithelial sheets play essential roles as selective barriers insulating the body from the environment and establishing distinct chemical compartments within it. In invertebrate epithelia, septate junctions (SJs) consist of large...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 282–290.
Published: 15 January 2015
.... Mechanistically, we show that loss of Cα, the predominant C-terminal p63 variant in epithelia, promotes the transcriptional activity of TAp63 and also impairs the dominant-negative activity of ΔNp63, thereby controlling p21 Waf1/Cip1 expression. We propose that the p63 C-terminus links cell cycle control and the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4279–4284.
Published: 15 November 2014
...@mail.med.upenn.edu ) Competing interests The authors declare no competing financial interests. 29 4 2014 5 9 2014 © 2014. Published by The Company of Biologists Ltd 2014 Caenorhabditis elegans EMT Delamination Epithelia Junction Ras We thank David Hall and the Center...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 2978–2983.
Published: 01 August 2014
...Lara C. Skwarek; Sarah L. Windler; Geert de Vreede; Gregory C. Rogers; David Bilder The Par-3/Par-6/aPKC complex is the primary determinant of apical polarity in epithelia across animal species, but how the activity of this complex is restricted to allow polarization of the basolateral domain is...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (14): 2796–2802.
Published: 15 July 2014
... competing financial interests. 11 11 2013 13 5 2014 © 2014. Published by The Company of Biologists Ltd 2014 Drosophila Endocytosis Epithelia Polarity Retromer The polarized distribution of proteins is central to biological function. Foundational work has identified...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (4): 889–898.
Published: 15 February 2014
...Sonia Hall; Courtney Bone; Kenzi Oshima; Liang Zhang; Molly McGraw; Bethany Lucas; Richard G. Fehon; Robert E. Ward, IV Polarized epithelia play crucial roles as barriers to the outside environment and enable the formation of specialized compartments for organs to carry out essential functions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (14): 2851–2855.
Published: 15 July 2013
...@mcdb.ucla.edu ; beitel@northwestern.edu ) Tubulogenesis Endothelia Epithelia Morphogenesis Lumen Tubes are the fundamental structural unit of many organs, including the vascular system, exocrine glands, digestive tract, lung and kidney. As metazoans evolved into creatures larger than...
Journal Articles
Journal: Development
Development (2013) 140 (1): 13–21.
Published: 01 January 2013
...; the second is the requirement for mutual antagonism between determinants that localise to opposite ends of the cell. In the C. elegans zygote, computer modelling suggests that domain size is simply determined by the relative amounts of anterior and posterior determinants. In fly epithelia, there...
Journal Articles
Journal: Development
Development (2012) 139 (5): 979–990.
Published: 01 March 2012
... a set of extracellular leucine-rich repeat only (eLRRon) proteins in C. elegans (LET-4 and EGG-6) that are expressed on the apical surfaces of epidermal cells and some tubular epithelia, including the excretory duct and pore. A previously characterized paralog, SYM-1, is also expressed in epidermal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (10): 1861–1871.
Published: 15 May 2007
... dynamic IPC morphogenesis, movement and cell-cell contacts during morphogenesis of the pupal retina. Adhesion BMP Dpp Epithelia Patterning Guiding cells to their correct positions within a patterned epithelium involves an intricate combination of cellular events. These events are...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (5): 999–1009.
Published: 01 March 2007
... equally to this work 14 12 2006 © 2007. 2007 MAGUK Cell junction Basolateral Epithelia Drosophila Trachea The function of organs such as the lung, kidney and vascular system depends on epithelial and endothelial tubes of specific sizes. However, the cell biological and...
Includes: Supplementary data