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Keywords: Epigenetic gene silencing
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Journal Articles
Lisa Redrup, Miguel R. Branco, Elizabeth R. Perdeaux, Christel Krueger, Annabelle Lewis, Fátima Santos, Takashi Nagano, Bradley S. Cobb, Peter Fraser, Wolf Reik
Journal:
Development
Development (2009) 136 (4): 525–530.
Published: 15 February 2009
... (ncRNA)Kcnq1ot1 regulates epigenetic gene silencing in an imprinted gene cluster in cis over a distance of 400 kb in the mouse embryo, whereas the silenced region extends over 780 kb in the placenta. Gene silencing by the Kcnq1ot1 RNA involves repressive histone modifications, including H3K9me2...
Includes: Supplementary data
