... for comparative studies centered on mammary gland development and cancer. Mammary organoid Equine Non-traditional model species Budding Epidermal growth factor Prolactin Cornell University http://dx.doi.org/10.13039/100007231 Albert C Bostwick Foundation Liz Hanson...

...Silvan Spiri; Simon Berger; Louisa Mereu; Andrew DeMello; Alex Hajnal ABSTRACT During Caenorhabditis elegans vulval development, the uterine anchor cell (AC) first secretes an epidermal growth factor (EGF) to specify the vulval cell fates and then invades the underlying vulval epithelium. By doing...

...Louisa Mereu; Matthias K. Morf; Silvan Spiri; Peter Gutierrez; Juan M. Escobar-Restrepo; Michael Daube; Michael Walser; Alex Hajnal ABSTRACT The anchor cell (AC) in C. elegans secretes an epidermal growth factor (EGF) homolog that induces adjacent vulval precursor cells (VPCs) to differentiate...

... γ1 chain drastically perturbed branching epithelial morphogenesis. Electron microscopy of the epithelial-mesenchymal interface showed that blocking antibodies disrupted the formation of the basement membrane. Epidermal growth factor was shown to increase the expression of nidogen in mesenchyme...

... by neighbouring parenchymal cells. These values are similar to those in vertebrate neural tissues where 50% or more of the cells die during normal development, suggesting that large-scale death is a normal feature of kidney development. We also show that in vivo treatment with epidermal growth factor inhibits...

... , W. A. and Young , M. W. ( 1987 ). Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus . Cell 51 , 539 – 548 . 10.1016/0092-8674(87)90123-1 Kidd , S. , Kelley , M. R. and Young , M. W. ( 1986...

... normally branch in the absence of mesenchymal cells. Combination of basement-membrane-like substratum (Matrigel) and epidermal growth factor (EGF) could substitute for the mesenchyme, the epithelium showing typical branching morphogenesis. Transforming growth factor a had the same effect as EGF. Matrigel...

...A. N. Corps; D. R. Brigstock; C. J. Littlewood; K. D. Brown 12s I-labelled epidermal growth factor ( 125 I-EGF) and 125 I-labelled insulin-like growth factor-I ( 12S I-IGF-I) bound to trophodenn cells from pig blastocysts obtained on days 15 –19 of pregnancy. Specific binding was detected...

... growth factor EGF mouse incisor eruption X-linked gene eyelid opening Epidermal growth factor (EGF), a polypeptide of low relative molecular mass (6054), was first isolated from mouse submandibular salivary gland ( Cohen, 1962 ). EGF has been found in virtually all murine and human body...

... ). The ontogeny of epidermal growth factor receptors during mouse development . Devl Biol . 103 , 62 – 70 . 10.1016/0012-1606(84)90007-1 Brown , R. , Gray , R. H. & Bernstein , I. A. ( 1985 ). Retinoids alter the direction of differentiation in primary cultures of cutaneous...

... mammalian development. 30 11 1987 © 1988 by Company of Biologists 1988 growth factor mammal epidermal growth factor EGF insulin-like growth factor IGF-I IGF-II transforming growth factor-beta TGF heparin-binding growth factor HBGF platelet-derived growth factor PDGF...