...Kazunari Matsuda; Tomoyuki Mikami; Shinya Oki; Hideaki Iida; Munazah Andrabi; Jeremy M. Boss; Katsushi Yamaguchi; Shuji Shigenobu; Hisato Kondoh To obtain insight into the transcription factor (TF)-dependent regulation of epiblast stem cells (EpiSCs), we performed ChIP-seq analysis of the genomic...

... and assayed. For the first one or two days after injection, more labeled cells survived in each chimeric embryo than in mouse EpiSC progeny ( Fig. 4 A), and some of these cells were found in the ICM ( Fig. 4 B). However, hiPSC-derived cells barely existed in ICM outgrowth after attachment ( Fig. 4 C) and were...

... with the dynamic cellular events occurring during gastrulation. * Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. 7 2 2013 © 2013. Published by The Company of Biologists Ltd 2013 EpiSC Primitive...

...Katsuhiko Hayashi; M. Azim Surani Pluripotent epiblast stem cells (EpiSCs) derived from postimplantation embryos exhibit properties that are characteristically different when compared with pluripotent embryonic stem cells (ESCs) derived from mouse blastocysts. However, EpiSCs are relatively less...