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Keywords: Eph
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Journal Articles
Journal: Development
Development (2016) 143 (14): 2603–2615.
Published: 15 July 2016
... are prevented from intermingling with adjacent cells. In this study, we show that the Eph receptor gene ephb4b is highly expressed in DFCs whereas ephrin ligand genes, including efnb2b , are expressed in cells next to the DFC cluster during zebrafish gastrulation. ephb4b knockdown or mutation and efnb2b...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (17): 3420–3430.
Published: 01 September 2014
.... , Vanderhaeghen P. ( 2003 ). Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes . Neuron 39 , 453 - 465 . 10.1016/S0896-6273(03)00440-9 Gale N. W. , Holland S. J. , Valenzuela D. M. , Flenniken A. , Pan L. , Ryan T. E...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (20): 4237–4245.
Published: 15 October 2013
... to altered refractive index and cataracts in humans and mice. References Abram C. L. , Courtneidge S. A. ( 2000 ). Src family tyrosine kinases and growth factor signaling . Exp. Cell Res. 254 , 1 – 13 . Arvanitis D. , Davy A. ( 2008 ). Eph/ephrin signaling: networks...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (22): 4105–4109.
Published: 15 November 2012
...Rüdiger Klein Eph receptors and their membrane-tethered ligands have important functions in development. Trans interactions of Eph receptors with ephrins at cell-cell interfaces promote a variety of cellular responses, including repulsion, attraction and migration. Eph-ephrin signalling can be bi...
Journal Articles
Journal: Development
Development (2010) 137 (24): 4295–4305.
Published: 15 December 2010
... receptor and dominant negative for the EphB2 receptor. The cytoplasmic domain of EphB2 is replaced with β-galactosidase, thereby blocking forward signaling but allowing reverse signaling via Eph ligands. To determine which receptor was required for proper branching, the compound mutant EphB2 lacZ...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (17): 2913–2921.
Published: 01 September 2009
... of Fibronectin (FN) depends on the FN receptor Integrinα5β1. Using in vivo imaging and genetic mosaics, our studies suggest that incipient Itgα5 clustering along the nascent border precedes matrix formation and is independent of FN binding. Integrin clustering can be initiated by Eph/Ephrin signaling...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 585–594.
Published: 15 February 2009
.... * Author for correspondence (e-mail: belmonte@salk.edu ) 8 12 2008 © 2009. 2009 Sall Townes-Brocks syndrome Hox Limb development Shh Eph Mouse The development of the vertebrate limb has long served as an experimental and conceptual model system with which to study...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (22): 4415–4420.
Published: 15 November 2006
...Audrey Dufour; Joaquim Egea; Klas Kullander; Rüdiger Klein; Pierre Vanderhaeghen Ephrin/Eph ligands and receptors are best known for their prominent role in topographic mapping of neural connectivity. Despite the large amount of work centered on ephrin/Eph-dependent signaling pathways in various...
Journal Articles
Journal: Development
Development (2006) 133 (9): 1845–1854.
Published: 01 May 2006
...Monica Boyle; Alan Nighorn; John B. Thomas The conserved Eph receptors and their Ephrin ligands regulate a number of developmental processes, including axon guidance. In contrast to the large vertebrate Eph/Ephrin family, Drosophila has a single Eph receptor and a single Ephrin ligand, both...
Journal Articles
Journal: Development
Development (2005) 132 (22): 4951–4962.
Published: 15 November 2005
... 123 , 179 -190. Brennan, C., Monschau, B., Lindberg, R., Guthrie, B., Drescher,U., Bonhoeffer, F. and Holder, N. ( 1997 ). Two Eph receptor tyrosine kinase ligands control axon growth and may be involved in the creation of the retinotectal map in the zebrafish. Development 124 , 655 -664...
Includes: Supplementary data