..., which is mutated in human mucociliary clearance disorder, and GemC1 (Gmnc or Lynkeas), previously implicated in cell cycle progression, are key regulators of multiciliated ependymal cell generation in the mouse brain. Overexpression and knockdown experiments show that Mcidas and GemC1 are sufficient...

... of basal body planar polarity, characterized by the anterior localization of the basal bodies in individual cells, was reported in the multiciliated ependymal cells that line the surface of brain ventricles. However, little is known about the cellular and molecular mechanisms by which this polarity...

... longitudinal sections. (D) Kupffer's vesicle;higher magnification (DAPI nuclear staining in blue). (B) Ependymal cells along the central canal bear cilia at 24 hpf (arrowheads). (E) Cross section at 44 hpf; cilia arise from all cells of the spinal central canal. (C) Cilia can also be seen in the pronephric...