..., which is mutated in human mucociliary clearance disorder, and GemC1 (Gmnc or Lynkeas), previously implicated in cell cycle progression, are key regulators of multiciliated ependymal cell generation in the mouse brain. Overexpression and knockdown experiments show that Mcidas and GemC1 are sufficient...

... of basal body planar polarity, characterized by the anterior localization of the basal bodies in individual cells, was reported in the multiciliated ependymal cells that line the surface of brain ventricles. However, little is known about the cellular and molecular mechanisms by which this polarity...

.... 2005 Cilia Pronephros Kupffer's vesicle Ependymal cell Spinal canal Kidney cyst Hydrocephalus Left-right asymmetry Cilia and flagella have well-established roles as motile and sensory organelles in various species; however, their function in vertebrate organogenesis is only now...