... License ( https://creativecommons.org/licenses/by/4.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Summary: The key developmental transcription factor eomesodermin can replace Wnt priming...

... that the original work is properly attributed. Summary: Expression of the mouse T-box factor Eomes is controlled by a key gene-proximal enhancer-like element, with changes in chromatin accessibility influencing its activity in definitive endoderm. Eomesodermin Enhancer Capture-C Nodal signalling...

...Sebastian J. Arnold; Ulf K. Hofmann; Elizabeth K. Bikoff; Elizabeth J. Robertson The T-box transcription factor eomesodermin ( Eomes ) has been implicated as an important component in germ layer induction and patterning in vertebrate embryos. In the mouse, Eomes is essential for development...

... differentiation. However,little is known about the genes that connect upstream regulatory genes, such as Pou4f2 with downstream effector genes responsible for RGC differentiation. The purpose of this study was to characterize the retinal function of eomesodermin (Eomes), a T-box transcription factor...

... and the trophectoderm (TE) that gives rise to the trophoblast lineage. Commitment to ICM lineage is attributed to the function of the two transcription factors, Oct4 (encoded by Pou5f1 ) and Nanog. However, a positive regulator of TE cell fate has not been described. The T-box protein eomesodermin (Eomes...

... in the zebrafish, eomesodermin ( eomes ). During oogenesis, the eomes transcript becomes localized to the cortex of the oocyte. After fertilization during early cleavage stages, eomes is expressed in a vegetal to animal gradient in the embryo, whereas Eomesodermin protein (Eom) is distributed cytoplasmically...

... box proteins Xbra, VegT and Eomesodermin resides in the DNA-binding domain, or T box. Binding site selection experiments show that the three proteins bind the same core sequence, but they select paired sites that differ in their orientation and spacing. Lysine 149 of Xbra is conserved in all Brachyury...

... detail than that of any other vertebrate morphogen. Xenopus Activin Morphogen gradient Eomesodermin Xbrachyury © 1999 by Company of Biologists 1999 22 08 1999 09 11 1999 * Author for correspondence (e-mail: [email protected] ) ...

...Fiona Stennard; Gilles Carnac; J. B. Gurdon ABSTRACT We have used differential display to identify genes inducible by activin and isolated a novel member of the T-box gene family that includes the Xenopus genes Xbrachyury and Eomesodermin . Here we show that this novel gene is unique within the T...