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Keywords: Enhancer blocking
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Journal Articles
A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication
Free
Journal:
Development
Development (2009) 136 (18): 3077–3087.
Published: 15 September 2009
... that normally drive Drosophila even skipped (eve) expression are located closer to the TER94 transcription start site than to that of eve . We discovered that the region between these genes has enhancer-blocking activity, and that this insulator region also mediates homing of P-element transgenes to the eve...
Includes: Supplementary data
Journal Articles
An endogenous Su(Hw) insulator separates the yellow gene from the Achaete-scute gene complex in Drosophila
Available to PurchaseAnton Golovnin, Inna Biryukova, Olga Romanova, Margarita Silicheva, Akeksander Parshikov, Ekaterina Savitskaya, Vincenzo Pirrotta, Pavel Georgiev
Journal:
Development
Development (2003) 130 (14): 3249–3258.
Published: 15 July 2003
... © 2003. 2003 Drosophila melanogaste Achaete-scute Complex Insulator Su(Hw) Mod(mdg4) Enhancer blocking Enhancer-mediated activation is a fundamental mechanism of gene regulation in eukaryotes. Enhancers can act over large distances to activate transcription, independent...
