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Keywords: Endosome
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Journal Articles
Journal: Development
Development (2006) 133 (23): 4679–4689.
Published: 1 December 2006
... transmembrane proteins marked with a single ubiquitin to the endosomal multivesicular body (MVB) and,subsequently, to the vacuole (yeast) or lysosome (animals), where they are degraded by proteases. Vps23p/TSG101 is a key component of the ESCRT I-III machinery in yeast and animals that recognizes mono...
Journal Articles
Journal: Development
Development (2003) 130 (13): 2819–2827.
Published: 1 July 2003
... activity and association with Notch-expressing cells that occur when Sca is ectopically expressed. Mosaic analysis found that the gp150 and sca genes were required in different cells from one another. Gp150 concentrated Sca protein in late endosomes. A model is proposed in which endosomal Sca and Gp150...