... in the degradation of extracellular macromolecules such as collagen IV. Moreover, MMPs such MMP9 and MMP13 have been shown to play a role in endochondral bone formation. It is therefore reasonable to assume that these enzymes may be involved in the degradation of the BM in bone vasculature. Another possible...

... reveals a feed-forward loop controlling FGFR3 signaling in growth plate chondrocytes. FGF signaling PTHLH IHH Skeletal development Endochondral bone formation Osteoblast Chondrocyte Mouse Human genetic disease and conditional gene inactivation experiments in mice have demonstrated...

... declare no competing financial interests. 5 1 2012 © 2012. Col11a2 HDAC4 SIK3 Chondrocyte hypertrophy Endochondral bone formation Knockout mouse Vertebrate bones develop through membranous or endochondral ossification. Except for craniofacial bones...

... that somatostatin is involved in the regulation of osteoblast differentiation during endochondral bone formation. Alternatively, somatostatin-binding sites may indeed be a characteristic of metaphyseal osteoblast precursors that distinguishes them from osteoblast precursors in other areas. An obvious...