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Keywords: Endocardial cushion
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Journal Articles
Journal: Development
Development (2006) 133 (18): 3607–3618.
Published: 15 September 2006
... swellings of extracellular matrix known as the endocardial cushions,the endothelial lining of the heart undergoes an epithelial to mesenchymal transition (EMT) to form the mesenchymal progenitors of the AV valves. Further growth and differentiation of these mesenchymal precursors results in the formation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (17): 3473–3484.
Published: 01 September 2006
..., Alk3 CKO embryos displayed multiple abnormalities in vascular development, including vessel remodeling and maturation, which contributed to severe abdominal hemorrhage. Alk3 CKO embryos also displayed defects in atrioventricular canal (AVC) endocardial cushion formation in the heart. Collectively, our...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (20): 5197–5209.
Published: 15 October 2004
...) overabundant endocardial cushions accompanied by ventricular septal defects, outflow tract abnormalities and atrio-ventricular (AV) valve dysplasia and (4) aberrant development of the compact myocardium. The dramatic enlargement of the endocardial cushions in the absence of Hhex is due to decreased apoptosis...
Journal Articles
Journal: Development
Development (2004) 131 (18): 4477–4487.
Published: 15 September 2004
... and proliferation. ‡ Authors for correspondence (e-mail: emorrise@mail.med.upenn.edu and philtucker@mail.utexas.edu ) * These authors contributed equally to this work † These laboratories contributed equally to this work 27 5 2004 © 2004. 2004 Foxp1 Endocardial cushion...
Journal Articles
Journal: Development
Development (2003) 130 (1): 209–220.
Published: 01 January 2003
... morphogenetic protein Endocardial cushion Outflow tract septation Persistent truncus arteriosus Hypomorph Semilunar valve © 2003. 2003 1 10 2002 * Author for correspondence (e-mail: klyons@mednet.ucla.edu ) Starting around day E9.5 in the mouse, the resident endocardium, under...