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Keywords: Enamel
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Journal Articles
Journal: Development
Development (2010) 137 (22): 3743–3752.
Published: 15 November 2010
... and mesenchymal stem cells in the proximal region of the tooth. Enamel, the hardest component of the tooth, is continuously deposited by stem cell-derived ameloblasts exclusively on the labial, or outer, surface of the tooth. The epithelial stem cells that are the ameloblast progenitors reside in structures...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (18): 3025–3035.
Published: 15 September 2010
..., regulation and function of the jagged 2 ( Jag2 ) gene, which encodes a ligand for the Notch family of receptors, in developing mouse teeth. Jag2 is expressed in epithelial cells that give rise to the enamel-producing ameloblasts from the earliest stages of tooth development. Tissue recombination experiments...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (2): 377–385.
Published: 15 January 2008
... by the absence of enamel on one side of the incisor. Here we report that loss-of-function of sprouty genes, which encode antagonists of receptor tyrosine kinase signaling,leads to bilateral enamel deposition, thus impeding incisor abrasion and resulting in unchecked tooth elongation. We demonstrate that sprouty...
Journal Articles
Journal Articles