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Keywords: Embryo genome activation
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Journal Articles
In collection:
Stem cells & regeneration
Eeva-Mari Jouhilahti, Elo Madissoon, Liselotte Vesterlund, Virpi Töhönen, Kaarel Krjutškov, Alvaro Plaza Reyes, Sophie Petropoulos, Robert Månsson, Sten Linnarsson, Thomas Bürglin, Fredrik Lanner, Outi Hovatta, Shintaro Katayama, Juha Kere
Journal:
Development
Development (2016) 143 (19): 3459–3469.
Published: 1 October 2016
... proportion of the genes that are upregulated in human embryo genome activation (EGA), whereas the previously predicted partial homeodomain isoform is largely inactive. Another PRD-like transcription factor, DPRX , is then upregulated as a powerful repressor of transcription. We propose a two-stage model...
Includes: Supplementary data