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Keywords: Ecdysone biosynthesis
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Journal Articles
The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels
Available to PurchaseV. Marcela Chávez, Guillermo Marqués, Jean Paul Delbecque, Kayta Kobayashi, Margarita Hollingsworth, John Burr, Jeanette E. Natzle, Michael B. O’Connor
Journal:
Development
Development (2000) 127 (19): 4115–4126.
Published: 1 October 2000
... in the dib gene, which encodes a cytochrome P450-like enzyme. Mutations in dib prevent dorsal closure, and interfere with embryonic cuticle deposition, midgut morphogenesis and head involution. Consistent with a potential role in ecdysone biosynthesis, RNA in situ hybridization reveals that two major...
