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Keywords: EcR
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Journal Articles
Journal: Development
Development (2024) 151 (12): dev202828.
Published: 17 June 2024
... require the hormone ecdysone (Ec) for growth but require a drop in circulating Ec levels to regenerate. Examining Ec dynamics more closely, we find that transcriptional activity of the Ec-receptor (EcR) drops in uninjured regions of wing discs, but simultaneously rises in cells around the injury-induced...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1788–1797.
Published: 15 May 2012
... indicate that steroid hormone-coupled control of let-7-C microRNAs is part of an ancestral pathway controlling the transition from larval-to-reproductive animal forms. UAS-EcR-RNAi, UAS-EcRA-W650A, UAS-EcRA, UAS-EcRB1 and UAS-EcRB2 transgenic fly strains were obtained from the Bloomington Stock...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (19): 3247–3256.
Published: 1 October 2009
... of incumbent remodeling neurons in the CNS is highly dependent on the ecdysone pathway, we investigated the role of ecdysone in the development of the adult-specific neuronal lineages using a dominant-negative construct of the ecdysone receptor(EcR-DN). When EcR-DN was expressed in clones of the adult-specific...
Journal Articles
Journal: Development
Development (2005) 132 (16): 3631–3642.
Published: 15 August 2005
... degeneration EcR The nervous system is generated by progressive developmental phenomena,such as cell division and growth, and regressive phenomena, such as cell death and pruning ( Cowan et al.,1984 ). One aspect of morphogenesis that is more pressing for neurons than other cell types...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (2): 271–284.
Published: 15 January 2003
...Lucy Cherbas; Xiao Hu; Igor Zhimulev; Elena Belyaeva; Peter Cherbas The three Drosophila EcR isoforms differ only at their N termini;thus, they share the conserved ligand-binding domain transcriptional activation function (AF2) and only differ in the unconserved A/B region, which contains a second...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (1): 1–11.
Published: 1 January 2001
... by Company of Biologists 2001 Drosophila Ecdysone Morphogenetic furrow BR-C EcR Hormones play essential roles in the development of many animals, particularly during postembryonic developmental changes, such as amphibian and insect metamorphosis, and mammalian puberty. While DNA-binding...