... is crucial for the first cleavage of mouse embryos ( Liu et al., 2012 ). In related studies on the early embryonic development of bovine SCNT embryos, researchers increased the expression of miR-34c or miR-449b in bovine fetal fibroblasts through the Tet-On system and then used the fibroblast as donor cells...

... Wnt signaling Early embryonic development Sea urchin The canonical Wnt pathway plays several key roles in early development of various organisms. It is involved, for example, in the establishment of embryonic axis polarities and germ layer specification (e.g. Logan et al., 1999...

... of development. These mice represent a specific model of disruption of the earliest stages of embryogenesis, implicating Zfp36l2, a probable mRNA-binding and destabilizing protein, in the physiological control of female fertility at the level of early embryonic development. This newly identified biological role...

... signalling Early embryonic development Mouse Bmp5 and Bmp7 may also synergize via the interaction of downstream effector molecules. Experiments using chimeric erythropoietin/TGF-β receptors show that homodimerization of type I receptors and hetero-oligomerization with type II receptors...