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Keywords: Ear
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Journal Articles
Journal: Development
Development (2011) 138 (17): 3689–3698.
Published: 1 September 2011
...Paola Betancur; Tatjana Sauka-Spengler; Marianne Bronner The otic placode, a specialized region of ectoderm, gives rise to components of the inner ear and shares many characteristics with the neural crest, including expression of the key transcription factor Sox10. Here, we show that in avian...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (5): 947–957.
Published: 1 March 2011
... in a murine Dachsous homolog, Dchs1 . Analysis of the phenotypes of Dchs1 mutant mice and comparisons with Fat4 mutant mice identify requirements for these genes in multiple organs, including the ear, kidney, skeleton, intestine, heart and lung. Dchs1 and Fat4 single mutants and Dchs1 Fat4 double mutants have...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (16): 2837–2848.
Published: 15 August 2009
...Leila Abbas; Tanya T. Whitfield Endolymph is the specialised extracellular fluid present inside the inner ear. In mammals, disruptions to endolymph homeostasis can result in either collapse or distension of the endolymphatic compartment in the cochlea, with concomitant hearing loss. The zebrafish...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (7): 1277–1286.
Published: 1 April 2006
...Rachael Brooker; Katsuto Hozumi; Julian Lewis Each of the sensory patches in the epithelium of the inner ear is a mosaic of hair cells and supporting cells. Notch signalling is thought to govern this pattern of differentiation through lateral inhibition. Recent experiments in the chick suggest...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (5): 929–940.
Published: 1 March 2003
...Keely S. Solomon; Tetsuhiro Kudoh; Igor B. Dawid; Andreas Fritz The otic placode is a transient embryonic structure that gives rise to the inner ear. Although inductive signals for otic placode formation have been characterized, less is known about the molecules that respond to these signals within...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4371–4386.
Published: 1 October 2002
... Audition Brain Branchial arch Dentition Ear Hematopoiesis Interneuron Leg Limb Neural crest Neural tube Olfaction Placode Telencephalon Tooth Tricho-dento-osseous syndrome (TDO) Split hand/split foot malformation (SHFM) GABAergic Otic Distal-less ( Dll ), as its name suggests...