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Keywords: ETS
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Journal Articles
Journal: Development
Development (2021) 148 (23): dev199465.
Published: 14 December 2021
... a rich dataset of Alk-responsive loci in the embryonic VM and functionally characterize the role of Kah in the regulation of embryonic midgut morphogenesis. Single cell ChIP Jelly belly Signaling TaDa Midgut constriction ETS Pointed Cancerfonden http://dx.doi.org/10.13039/501100002794...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (12): dev199542.
Published: 28 June 2021
.... Mariadason ABSTRACT Ets homologous factor (EHF) is a member of the epithelial-specific Ets (ESE) family of transcription factors. To investigate its role in development and epithelial homeostasis, we generated a series of novel mouse strains in which the Ets DNA-binding domain of Ehf was deleted in all...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (12): 2632–2642.
Published: 15 June 2013
... partner Lmo2. Thus, the two ETS factors Fli1 and Etv6, which drives the VEGFA expression in both somites and the DLP, sit at the top of the adult haemangioblast gene regulatory network (GRN). Furthermore, Gata2 is initially activated by Fli1 but later maintained by another ETS factor, Etv2. We also...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (7): 1421–1432.
Published: 1 April 2011
...-negative form of the sole Ci -FGFR (FGFR DN ) in the pigment cell precursors ( Davidson et al., 2006 ). Targeted expression of FGFR DN resulted in larvae lacking one or both pigment cells, showing normal morphology of the palps, tail and sensory vesicle. The Ci - tyrp1a and Ci-tyr 5′flanking...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (22): 4023–4032.
Published: 15 November 2007
... only. Whereas the enhancers of both genes contain critical and interchangeable GATA sites, their distinct patterns of activation stem from the additional presence of two Ets sites in the Ci-otx enhancer. Initially characterized as activating elements in the neural lineages, these Ets sites additionally...
Journal Articles
Journal: Development
Development (2007) 134 (9): 1703–1712.
Published: 1 May 2007
... expression in Gata2 -GFP knock-in embryos. Using founder transgenic analyses, we identified a Gata2 endothelium enhancer in the fourth intron and found that Gata2 regulation by this enhancer is restricted to the endocardial, lymphatic and vascular endothelium. Whereas disruption of three ETS-binding motifs...
Journal Articles
Journal: Development
Development (2005) 132 (15): 3493–3504.
Published: 1 August 2005
... understood. During Drosophila oogenesis, a small group of cells called border cells exit the follicular epithelium to perform a stereotypic, invasive migration. We find that the ETS transcription factor Yan is required for border cell migration and that Yan expression is spatiotemporally regulated as border...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 1047–1056.
Published: 1 March 2005
...Elizabeth R. Leight; Danielle Glossip; Kerry Kornfeld The LIN-1 ETS transcription factor inhibits vulval cell fates during Caenorhabditis elegans development. We demonstrate that LIN-1 interacts with UBC-9, a small ubiquitin-related modifier (SUMO) conjugating enzyme. This interaction is mediated...
Journal Articles
Journal: Development
Development (2004) 131 (16): 3885–3896.
Published: 15 August 2004
... involved in FGF signaling and found that several members of the Fgf8 synexpression group are co-expressed with Scx in the dorsal sclerotome. Of particular interest were the Ets transcription factors Pea3 and Erm , which function as transcriptional effectors of FGF signaling. We show here...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4907–4917.
Published: 15 October 2003
... in its intronic sequence and that these multiple FREs comprise Ets-binding and Tcf/Lef-binding motifs that lie in juxtaposition. Functional and physical analyses indicate that signaling pathways of Fgf, Bmp and Wnt are integrated on these FREs to regulate the expression of Xcad3 in the posterior neural...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4387–4397.
Published: 1 October 2002
... specifically to the cement gland. Within this region, putative binding sites for Ets and ATF/CREB transcription factors are both necessary and sufficient to drive cement gland-specific expression, and cooperate to do so. Furthermore, while the putative ATF/CREB factor is activated by Otx2, a factor acting...