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Keywords: ES cell
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Journal: Development
Development (2009) 136 (12): 2069–2079.
Published: 15 June 2009
... ). We previously reported a defined culture condition that allows the selective differentiation of mouse ES cells into goosecoid + (Gsc + ) mesendodermal cells, which subsequently differentiate into E-cadherin + (E-cad; Cdh1 - Mouse Genome Informatics) definitive endoderm and E-cad - mesoderm( Tada et...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (2006) 133 (19): 3787–3796.
Published: 1 October 2006
... the functional competence of differentiating ES cells, reflected by their failure to generate Flk1 + mesodermal precursors and subsequent mature mesodermal lineages. Microarray analysis at various times during early differentiation reveal that mesoderm- and endoderm-associated genes fail to be induced...
Includes: Supplementary data
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Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (16): 3473–3483.
Published: 15 August 1999
... rise to the endothelial and haematopoietic cells of the yolk sac vasculature, is derived from embryonic stem (ES) cells. The ES cells were stably transfected and express either the full-length type II binding receptor or a kinase-deficient mutant of this receptor. Examination of yolk sacs from...
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Journal: Development
Development (1998) 125 (5): 845–856.
Published: 1 March 1998
... the mechanisms involved in this neural function and specifically the requirement for Otx2 in the visceral endoderm and the neuroectoderm using chimeric analysis in mice and explant recombination assay. Analyses of chimeric embryos composed of more than 90% of Otx2 − / − ES cells identified an essential function...
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Journal Articles
Journal: Development
Development (1996) 122 (10): 3185–3194.
Published: 1 October 1996
...Lionel Larue; Christopher Antos; Stefan Butz; Otmar Huber; Véronique Delmas; Mara Dominis; Rolf Kemler ABSTRACT We have produced null mutant mouse embryonic stem cells for the cell adhesion molecule E-cadherin. Such E-cadherin −/− ES cells are defective in cell aggregation; this defect can...
Journal Articles
Journal: Development
Development (1996) 122 (10): 2977–2986.
Published: 1 October 1996
... 07 1996 © 1996 by Company of Biologists 1996 BMP2 Gene targeting ES cell Cardiac development The bone morphogenetic proteins (BMPs) are a group of secreted signaling proteins that were originally identified by their ability to induce ectopic bone formation when implanted...
Journal Articles
Journal: Development
Development (1995) 121 (3): 877–886.
Published: 1 March 1995
... (ES) cells colonise wild-type embryos, but in chimeras at 10.5 days post coitum (dpc) onwards they are found predominantly in the distal tail, while trunk paraxial and lateral mesoderm are deficient in T/T cells (Wilson, V., Rashbass, P. and Beddington, R. S. P. (1992) Development 117, 1321-1331...
Journal Articles
Journal: Development
Development (1993) 117 (4): 1321–1331.
Published: 1 April 1993
...Valerie Wilson; Penny Rashbass; Rosa S. P. Beddington To investigate T(Brachyury) gene function, a chimeric analysis of midgestation (9.5–11.5 days post coitum) embryos has been performed. Embryonic stem (ES) cell lines homozygous or heterozygous for the T gene have been introduced into wild-type...
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