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Journal Articles

The enteric nervous system in zebrafish larvae can regenerate via migration into the ablated area and proliferation of neural crest-derived cells

Maria Ohno, Masataka Nikaido, Natsumi Horiuchi, Koichi Kawakami, Kohei Hatta
Journal: Development
Development (2021) 148 (2): dev195339.
DOI: https://doi.org/10.1242/dev.195339
Published: 26 January 2021
...Maria Ohno; Masataka Nikaido; Natsumi Horiuchi; Koichi Kawakami; Kohei Hatta ABSTRACT The enteric nervous system (ENS), which is derived from neural crest, is essential for gut function, and its deficiency causes severe congenital diseases. Since the capacity for ENS regeneration in mammals...
View article titled, The enteric nervous system in zebrafish larvae can regenerate via migration into the ablated area and proliferation of neural crest-derived cells
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Includes: Supplementary data
Journal Articles

Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis

Jun Lei, Marthe J. Howard
Journal: Development
Development (2011) 138 (21): 4789–4800.
DOI: https://doi.org/10.1242/dev.060053
Published: 1 November 2011
...Jun Lei; Marthe J. Howard Targeted deletion of the bHLH DNA-binding protein Hand2 in the neural crest, impacts development of the enteric nervous system (ENS), possibly by regulating the transition from neural precursor cell to neuron. We tested this hypothesis by targeting Hand2 deletion in nestin...
View article titled, Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis
Click here to open pdf in another window PDF for Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis
Journal Articles

GDNF availability determines enteric neuron number by controlling precursor proliferation

Scott Gianino, John R. Grider, Jennifer Cresswell, Hideki Enomoto, Robert O. Heuckeroth
Journal: Development
Development (2003) 130 (10): 2187–2198.
DOI: https://doi.org/10.1242/dev.00433
Published: 15 May 2003
...Scott Gianino; John R. Grider; Jennifer Cresswell; Hideki Enomoto; Robert O. Heuckeroth To clarify the role of Ret signaling components in enteric nervous system(ENS) development, we evaluated ENS anatomy and intestinal contractility in mice heterozygous for Ret, GFRα1 and Ret ligands...
View article titled, GDNF availability determines enteric neuron number by controlling precursor proliferation
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