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Keywords: ELT-2
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Journal Articles

PAR-4/LKB1 prevents intestinal hyperplasia by restricting endoderm specification in Caenorhabditis elegans embryos

Flora Demouchy, Ophélie Nicolle, Grégoire Michaux, Anne Pacquelet
Journal: Development
Development (2024) 151 (1): dev202205.
https://doi.org/10.1242/dev.202205
Published: 4 January 2024
... of the intestinal cell fate factors end-1 and elt-2 outside the E lineage. Notably, par-4 mutants also display reduced expression of end-1 and elt-2 inside the E lineage. Our work thereby unveils an essential and dual role of PAR-4, which both restricts intestinal specification to the E lineage and ensures its...
View article titled, PAR-4/LKB1 prevents intestinal hyperplasia by restricting endoderm specification in Caenorhabditis elegans embryos
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Includes: Supplementary data
Journal Articles

How affinity of the ELT-2 GATA factor binding to cis- acting regulatory sites controls Caenorhabditis elegans intestinal gene transcription

In collection:
Chromatin and epigenetics
Brett R. Lancaster, James D. McGhee
Journal: Development
Development (2020) 147 (14): dev190330.
https://doi.org/10.1242/dev.190330
Published: 24 July 2020
...Brett R. Lancaster; James D. McGhee ABSTRACT We define a quantitative relationship between the affinity with which the intestine-specific GATA factor ELT-2 binds to cis -acting regulatory motifs and the resulting transcription of asp-1 , a target gene representative of genes involved...
View article titled, How affinity of the <span class="search-highlight">ELT</span>-<span class="search-highlight">2</span> GATA factor binding to cis- acting regulatory sites controls Caenorhabditis elegans intestinal gene transcription
Open the PDF for How affinity of the <span class="search-highlight">ELT</span>-<span class="search-highlight">2</span> GATA factor binding to cis- acting regulatory sites controls Caenorhabditis elegans intestinal gene transcription in another window
Includes: Supplementary data
Journal Articles

The function and regulation of the GATA factor ELT-2 in the C. elegans endoderm

Tobias Wiesenfahrt, Janette Y. Berg, Erin Osborne Nishimura, Adam G. Robinson, Barbara Goszczynski, Jason D. Lieb, James D. McGhee
Journal: Development
Development (2016) 143 (3): 483–491.
https://doi.org/10.1242/dev.130914
Published: 1 February 2016
...Tobias Wiesenfahrt; Janette Y. Berg; Erin Osborne Nishimura; Adam G. Robinson; Barbara Goszczynski; Jason D. Lieb; James D. McGhee ELT-2 is the major regulator of genes involved in differentiation, maintenance and function of C. elegans intestine from the early embryo to mature adult. elt-2...
View article titled, The function and regulation of the GATA factor <span class="search-highlight">ELT</span>-<span class="search-highlight">2</span> in the C. elegans endoderm
Open the PDF for The function and regulation of the GATA factor <span class="search-highlight">ELT</span>-<span class="search-highlight">2</span> in the C. elegans endoderm in another window
Includes: Supplementary data