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Keywords: EGF
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Journal Articles
Journal: Development
Development (2012) 139 (9): 1611–1619.
Published: 1 May 2012
... rhomboid regulates EGF signaling to specify distinct cell types. Recently, we identified a CRM that activates rhomboid expression and thereby EGF secretion from a subset of abdominal sensory organ precursor cells (SOPs) to induce an appropriate number of lipid-processing cells called oenocytes. Here, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (23): 5099–5112.
Published: 1 December 2011
... into normal and dysregulated nephrogenesis, as well as into regenerative processes that follow kidney injury. In this study, we found that the mouse CITED1 + progenitor compartment is maintained in response to receptor tyrosine kinase (RTK) ligands that activate both FGF and EGF receptors. This RTK signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (13): 2153–2164.
Published: 1 July 2009
... follicle epithelium from interfollicular epidermis. Although many developmental signalling pathways are implicated in follicle morphogenesis,the role of epidermal growth factor (EGF) and keratinocyte growth factor (KGF,also known as FGF7) receptors are not defined. EGF receptor (EGFR) ligands have...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (16): 2947–2958.
Published: 15 August 2007
... with a potent upregulation of several members of the EGF family of mitogens. Moreover, loss of TAF4 leads to malignant transformation of chemically induced papillomas and the appearance of invasive melanocytic tumours. Together, our results show that TAF4 is an important regulator of keratinocyte proliferation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (1): 143–151.
Published: 1 January 2004
...Byung Joon Hwang; Paul W. Sternberg During C. elegans vulval development, the anchor cell (AC) in the somatic gonad expresses lin-3 , activating the EGF receptor signaling pathway in vulval precursor cells (VPCs) and thereby inducing and patterning VPCs. Previous studies with lin-3 mutants...
Journal Articles
Journal: Development
Development (2003) 130 (19): 4553–4566.
Published: 1 October 2003
...: Molecular Neuropathology Group, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan 12 6 2003 © 2003. 2003 EGF Muscle Neurons Behavior Vulva G protein C. elegans vulva development is used as a model system to study the regulation of cell fate...
Journal Articles
Journal: Development
Development (2003) 130 (1): 57–69.
Published: 1 January 2003
... to specificity of this class of mediator protein. * Author for correspondence (e-mail: pws@caltech.edu ) 4 10 2002 © 2003. 2003 EGF RAS LET-23 SOP-1 DPY-22 Mediator Vulva C. elegans Activation of signal transduction pathways by growth factors is frequently used...
Journal Articles
Journal: Development
Development (2002) 129 (18): 4261–4269.
Published: 15 September 2002
... gene blistered . We further show that attenuation of Dpp signalling in the AP organiser is also col dependent and, in conjunction with Vein upregulation, required for formation of L4 vein. A model recapitulating the molecular interplay between the Hh, Dpp and EGF signalling pathways in the wing AP...
Journal Articles
Journal: Development
Development (2002) 129 (10): 2541–2553.
Published: 15 May 2002
...), BMP4 (75 ng/μl; a kind gift from J. Wozney, Genetics Institute, Cambridge, MA), EGF (25 ng/μl; Boehringer Mannheim GmbH, Germany), FGF10 (25 ng/μl; R&D), SHH (50 ng/μl; R&D) or bovine serum albumin (BSA, 1 μg/μl; Sigma). The NIH3T3 cell line expressing Wnt6 gene was a kind gift from Seppo...
Journal Articles
Journal: Development
Development (1993) 119 (Supplement): 9–18.
Published: 1 December 1993
... precursors to assume the 1° and 2° vulval fates. This inductive signal is an EGF-like growth factor encoded by the gene lin-3. An inhibitory signal mediated by lin-15 , and which may originate from the surrounding epidermis, prevents the vulval precursors from assuming vulval fates in the absence...