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Keywords: Drosophila ovary
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Journal Articles

Yorkie and Hedgehog independently restrict BMP production in escort cells to permit germline differentiation in the Drosophila ovary

Jianhua Huang, Amy Reilein, Daniel Kalderon
Journal: Development
Development (2017) 144 (14): 2584–2594.
https://doi.org/10.1242/dev.147702
Published: 15 July 2017
... signaling pathways guide the maintenance, differentiation and proliferation of somatic and germline stem cells of the Drosophila germarium. Yorkie Hedgehog signaling Stem cell niche Drosophila ovary Escort cell National Institutes of Health 10.13039/100000002 GM079351...
View article titled, Yorkie and Hedgehog independently restrict BMP production in escort cells to permit germline differentiation in the <span class="search-highlight">Drosophila</span> <span class="search-highlight">ovary</span>
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Includes: Supplementary data
Journal Articles

Control of germline stem cell differentiation by Polycomb and Trithorax group genes in the niche microenvironment

Xuewen Li, Fu Yang, Hongyan Chen, Bowen Deng, Xinghua Li, Rongwen Xi
Journal: Development
Development (2016) 143 (19): 3449–3458.
https://doi.org/10.1242/dev.137638
Published: 1 October 2016
... embryonic development, but whether this function module has a role in adult tissues is unclear. Here, we report that in the Drosophila ovary, disruption of the Polycomb repressive complex 1 (PRC1), specifically in the supporting escort cells, causes blockage of cystoblast differentiation and germline stem...
View article titled, Control of germline stem cell differentiation by Polycomb and Trithorax group genes in the niche microenvironment
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Includes: Supplementary data
Journal Articles

TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation

Pei Sun, Zhenghui Quan, Bodi Zhang, Tuoqi Wu, Rongwen Xi
Journal: Development
Development (2010) 137 (15): 2461–2469.
https://doi.org/10.1242/dev.051466
Published: 1 August 2010
.... Here, we describe a novel role of TSC1/2 in controlling stem cell maintenance. We show that in the Drosophila ovary, disruption of either the Tsc1 or Tsc2 gene in germline stem cells (GSCs) leads to precocious GSC differentiation and loss. The GSC loss can be rescued by treatment with TORC1 inhibitor...
View article titled, TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation
Open the PDF for TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation in another window
Includes: Supplementary data