... morphogenesis. In the mouse, the genes of the spontaneous mutations Tabby ( Ta ) and downless ( dl ) were identified as homologs of ED1 and EDAR , respectively. To gain insight into the function of this signaling pathway in development of skin and hair follicles, we analyzed the expression and regulation of Eda...

...Abigail S. Tucker; Denis J. Headon; Pascal Schneider; Betsy M. Ferguson; Paul Overbeek; Jurg Tschopp; Paul T. Sharpe ABSTRACT tabby and downless mutant mice have apparently identical defects in teeth, hair and sweat glands. Recently, genes responsible for these spontaneous mutations have been...