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Keywords: Dorsal
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Journal Articles
Journal: Development
Development (2018) 145 (9): dev156018.
Published: 25 April 2018
... ). In the Drosophila wing disc epithelium, Tolls are involved in these processes. Genetic inference indicates that Spz may function via Toll-3 and Toll-9 to trigger, via Dorsal and Dif, the Reaper-induced apoptosis of loser mutant cells, or via Toll-2, -4, -8 and -9 to induce the apoptosis of loser wild-type cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (23): 4450–4461.
Published: 01 December 2017
...Sophia N. Carrell; Michael D. O'Connell; Thomas Jacobsen; Amy E. Pomeroy; Stephanie M. Hayes; Gregory T. Reeves The transcription factor NF-κB plays an important role in the immune system, apoptosis and inflammation. Dorsal, a Drosophila homolog of NF-κB, patterns the dorsal-ventral axis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (16): 3032–3039.
Published: 15 August 2012
...Aharon Helman; Bomyi Lim; María José Andreu; Yoosik Kim; Tatyana Shestkin; Hang Lu; Gerardo Jiménez; Stanislav Y. Shvartsman; Ze’ev Paroush The dorsoventral (DV) axis of the Drosophila embryo is patterned by a nuclear gradient of the Rel family transcription factor, Dorsal (Dl), that activates...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (22): 4409–4414.
Published: 15 November 2006
...Girish S. Ratnaparkhi; Songtao Jia; Albert J. Courey The Rel family transcription factor Dorsal patterns the dorsoventral axis of the Drosophila embryo by activating genes such as twist and snail and repressing genes such as decapentaplegic and zerknüllt . Dorsal represses transcription...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (15): 3419–3429.
Published: 01 August 2005
...Atish Ganguly; Jin Jiang; Y. Tony Ip The maternal Toll signaling pathway sets up a nuclear gradient of the transcription factor Dorsal in the early Drosophila embryo. Dorsal activates twist and snail , and the Dorsal/Twist/Snail network activates and represses other zygotic genes to form...
Journal Articles
Journal: Development
Development (2004) 131 (10): 2387–2394.
Published: 15 May 2004
... when tested in vivo. In the present study, co-regulated neurogenic enhancers that are activated by intermediate levels of the Dorsal regulatory gradient are shown to contain several shared sequence motifs. These motifs permitted the identification of new neurogenic enhancers with high precision: five...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (24): 5635–5645.
Published: 15 December 2002
...Andy J. Chang; Donald Morisato Dorsoventral polarity of the Drosophila embryo requires maternal spätzle-Toll signaling to establish a nuclear gradient of Dorsal protein. The shape of this gradient is altered in embryos produced by females carrying dominant alleles of easter (ea D ) . The easter...
Journal Articles
Journal: Development
Development (2002) 129 (14): 3411–3419.
Published: 15 July 2002
...Angelike Stathopoulos; Michael Levine Differential activation of the Toll receptor leads to the formation of a broad Dorsal nuclear gradient that specifies at least three patterning thresholds of gene activity along the dorsoventral axis of precellular embryos. We investigate the activities...
Journal Articles
Journal: Development
Development (2002) 129 (7): 1785–1793.
Published: 01 April 2002
...John Cowden; Michael Levine The maternal Dorsal nuclear gradient initiates the differentiation of the mesoderm, neurogenic ectoderm and dorsal ectoderm in the precellular Drosophila embryo. Each tissue is subsequently subdivided into multiple cell types during gastrulation. We have investigated...
Journal Articles
Journal: Development
Development (2001) 128 (23): 4729–4736.
Published: 01 December 2001
... Tube and protein kinase Pelle. Signaling through these components directs degradation of the IκB-like inhibitor Cactus and nuclear translocation of the Rel protein Dorsal. Here we show through confocal immunofluorescence microscopy that Pelle functions to downregulate the signal-dependent...
Journal Articles
Journal: Development
Development (1992) 116 (Supplement): 173–181.
Published: 01 April 1992
...Christine Thisse; Bernard Thisse Maternal genes involved in dorsoventral (D/V) patterning of the Drosophila embryo interact to establish a stable nuclear concentration gradient of the Dorsal protein which acts as the morphogen along this axis. This protein belongs to the rel proto-oncogene and NF...