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Keywords: Dopamine
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Journal Articles
Journal: Development
Development (2017) 144 (5): 916–927.
Published: 01 March 2017
... that subdivides the mouse mesodiencephalic floor plate into two microdomains, each giving rise to distinct types of neurons, is identified. Floor plate Dopamine Subthalamic Fate map Boundary Mouse Premammillary Borders are defined when territorial disputes are resolved. This is also the case...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1464–1474.
Published: 01 May 2016
... of spinal motor neurons following mechanical lesion or genetic ablation occurs at the expense of oligodendrogenesis and is promoted by the innate immune system. Dopamine Macrophage Microglia Nitroreductase Hb9 Olig2 Sox10 In contrast to mammals, adult zebrafish are capable...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (3): 516–529.
Published: 01 February 2016
... Glutamate Dopamine Serotonin Midbrain Hindbrain Mouse Chicken Midbrain dopaminergic (DA) and dorsal raphe serotonergic (5-HT) neurons regulate responses to reward and punishment, associative learning, mood, and coordination of voluntary movements. Function of these monoaminergic pathways...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4554–4564.
Published: 15 November 2013
.... Published by The Company of Biologists Ltd 2013 Midbrain Dopamine Migration Neuritogenesis Mouse We next examined whether the meninges are capable of promoting the migration of TH + cells in a CXCR4-dependent manner and performed co-cultures of E11.5 or E12.5 meninges and VM...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (16): 3373–3384.
Published: 15 August 2013
... to this work Competing interests statement The authors declare no competing financial interests. 7 6 2013 © 2013. Published by The Company of Biologists Ltd 2013 Dopamine Midbrain Neurodegeneration Substantia nigra Transcription Mouse The pathological...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (6): 1159–1169.
Published: 15 March 2013
.... , Richardson E. , et al . ( 2011 ). Prolonged membrane depolarization enhances midbrain dopamine neuron differentiation via epigenetic histone modifications . Stem Cells 29 , 1861 – 1873 . Hicks C. W. , Pandya M. M. , Itin I. , Fernandez H. H. ( 2011 ). Valproate...
Journal Articles
Journal: Development
Development (2012) 139 (18): 3316–3325.
Published: 15 September 2012
... midline Dopamine Drosophila gooseberry Neuron A key aspect of neurogenesis concerns how neural precursors are generated and acquire specific fates. The simplified view is that patterning proteins, consisting of intercellular signaling pathway components and transcription factors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (23): 5213–5222.
Published: 01 December 2011
...Frank M. J. Jacobs; Jesse V. Veenvliet; Wadia H. Almirza; Elisa J. Hoekstra; Lars von Oerthel; Annemarie J. A. van der Linden; Roel Neijts; Marian Groot Koerkamp; Dik van Leenen; Frank C. P. Holstege; J. Peter H. Burbach; Marten P. Smidt Development of meso-diencephalic dopamine (mdDA) neurons...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (11): 2171–2183.
Published: 01 June 2011
... genes act together to control H-cell gene expression. The l(1)sc bHLH gene is required for all H-cell-specific gene transcription, whereas tailup acts in parallel to l(1)sc and controls genes involved in dopamine metabolism. SoxNeuro functions downstream of l(1)sc and controls expression of a peptide...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (24): 4127–4134.
Published: 15 December 2010
... are restricted to the forebrain, whereas all other regions are essentially quiescent. However, ablation of midbrain dopamine neurons in newts induced ependymoglia cells in the normally quiescent midbrain to proliferate and to undertake full dopamine neuron regeneration. Using oligonucleotide microarrays, we have...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (14): 2363–2373.
Published: 15 July 2009
...Frank M. J. Jacobs; Annemarie J. A. van der Linden; Yuhui Wang; Lars von Oerthel; Hei Sook Sul; J. Peter H. Burbach; Marten P. Smidt The orphan nuclear receptor Nurr1 is essential for the development of meso-diencephalic dopamine (mdDA) neurons and is required, together with the homeobox...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 531–540.
Published: 15 February 2009
... underlying development of mdDA neurons in vivo, and the programming of stem cells as a future cell replacement therapy for Parkinson's disease. * Author for correspondence (e-mail: m.p.smidt-2@umcutrecht.nl ) 12 11 2008 © 2009. 2009 DA phenotype Dat Dopamine Parkinson's disease...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (20): 3401–3413.
Published: 15 October 2008
... hydroxylase (TH)-positive group 2 DA neurons and a moderate increase in the number of group 3-6 DA cells( Figs 1B,D,F and see Fig. S1 in the supplementary material ). Similarly, a two-fold increase in dopamine transporter ( dat ; slc6a3 )-positive neurons was observed, starting from the earliest stage...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (24): 4417–4426.
Published: 15 December 2007
... as a critical determinant underlying Fezl- and PAC1-mediated differentiation. * Author for correspondence (e-mail: gil.levkowitz@weizmann.ac.il ) 19 9 2007 © 2007. 2007 Neural development Dopamine Oxytocin The hypothalamus is a complex brain structure that regulates endocrine...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (15): 2881–2887.
Published: 01 August 2007
... immunohistochemical analyses with antibodies raised against tyrosine hydroxylase (TH, the rate-limiting enzyme in dopamine biosynthesis), Nurr1 and engrailed 1( Arenas, 2005 ). We focused our study on 780 ventral diencephalic/mesencephalic TH + cells (see Fig. S1 in the supplementary material ), which were...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (14): 2673–2684.
Published: 15 July 2007
... contributed equally to this work and should be considered shared first author 3 5 2007 © 2007. 2007 Pitx3 Retinoic acid Aldehyde dehydrogenase Development Midbrain Dopamine Parkinson's disease Ahd2 aldh1a1 Mouse Parkinson's disease (PD) is a common progressive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (23): 5185–5197.
Published: 01 December 2005
... and m.placzek@sheffield.ac.uk ) 19 9 2005 ©2005. 2005 Shh Bmp7 Chick Dopamine Hypothalamus During development of the central nervous system (CNS), neurons are generated under the influence of secreted inductive signals( Liu and Joyner, 2001 ; Jessell, 2002 ). Signals derive from...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3671–3680.
Published: 01 August 2004
...) in Helisoma and dopamine in Lymnaea ] that inhibit larval development acting via ergometrine-sensitive internal receptors. Thus, the novel regulatory mechanism in larval development of molluscs is suggested and compared with the phenomenon of dauer larvae formation in the nematode Caenorhabditis elegans...
Journal Articles
Journal: Development
Development (2003) 130 (11): 2535–2542.
Published: 01 June 2003
...Pepijn van den Munckhof; Kelvin C. Luk; Line Ste-Marie; Jane Montgomery; Pierre J. Blanchet; Abbas F. Sadikot; Jacques Drouin Mesencephalic dopaminergic (MesDA) neurons play crucial roles in motor and behavioral processes; their loss in Parkinson's disease (PD) results in striatal dopamine (DA...