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Keywords: Distal-less
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Journal Articles
Journal: Development
Development (2019) 146 (9): dev169367.
Published: 9 May 2019
... differentiation are still poorly understood. Using CRISPR-Cas9 we re-examine the function of Distal-less (Dll) as an activator or repressor of eyespots, a topic that remains controversial. We show that the phenotypic outcome of CRISPR mutations depends upon which specific exon is targeted. In Bicyclus anynana...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (9): 1755–1765.
Published: 1 May 2007
.... References Acampora, D., Merlo, G. R., Paleari, L., Zeraga, B.,Postiglione, M. P., Mantero, S., Bober, E., Barbieri, O., Simeone, A. and Levi, G. ( 1999 ). Craniofacial, vestibular and bone defects in mice lacking the Distal-less -related gene Dlx5. Development 126 , 3795 -3809. Anderson, S...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (1): 117–127.
Published: 1 January 2006
... genitalia, the latter also requiring abdominal-A ( abd-A ), whereas Abd-B r shapes male genitalia (A9 in males). Although Abd-B r represses Abd-B m in the embryo, in at least part of the male A9 such regulation does not occur. In the male A9, some Abd-B m – r – or Abd-B r – clones activate Distal-less...
Journal Articles
Journal: Development
Development (2005) 132 (23): 5261–5270.
Published: 1 December 2005
... of the Drosophila embryo through the target gene Distal-less. Cell 71 , 437 -450. Weatherbee, S. D., Nijhout, H. F., Grunert, L. W., Halder, G.,Galant, R., Selegue, J. and Carroll, S. ( 1999 ). Ultrabithorax function in butterfly wings and the evolution of insect wing patterns. Curr. Biol. 9 , 109 -115...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (7): 1579–1590.
Published: 1 April 2005
.... and Westerfield,M. ( 1994 ). Combinatorial expression of three zebrafish genes related to distal-less: part of a homeobox gene code for the head. J. Neurosci. 14 , 3475 -3486. Ashery-Padan, R. and Gruss, P. ( 2001 ). Pax6 lights-up the way for eye development. Curr. Opin. Cell Biol. 13 , 706 -714...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (2): 371–382.
Published: 15 January 2005
... placode Genetic network Paired Fibroblast growth factor forkhead distal-less msxC Pax proteins are key regulators of developmental processes including specification, differentiation, growth, survival, migration and morphogenesis( Chi and Epstein, 2002 ; Dahl et al., 1997 ; Mansouri...
Journal Articles
Journal: Development
Development (2004) 131 (4): 767–774.
Published: 15 February 2004
... of secreted signaling proteins that direct localized expression of transcription factors. The Drosophila homeodomain protein Distal-less is expressed in the leg primordia and required for formation of legs, but not wings. The homeodomain protein Nubbin is expressed in the wing primordia and required...
Journal Articles
Journal: Development
Development (2003) 130 (6): 1171–1180.
Published: 15 March 2003
... to differentiation of antenna-specific characteristics. Antenna-specific expression of dan and danr depends on a regulatory hierarchy involving homothorax and Distal-less , as well as cut and spineless . We propose that dan and danr are effector genes that act downstream of these genes to control differentiation...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4371–4386.
Published: 1 October 2002
...Grace Panganiban; John L. R. Rubenstein Distal-less is the earliest known gene specifically expressed in developing insect limbs; its expression is maintained throughout limb development. The homeodomain transcription factor encoded by Distal-less is required for the elaboration of proximodistal...
Journal Articles
Journal: Development
Development (2002) 129 (15): 3555–3561.
Published: 1 August 2002
... a prominent ventral branch found in the second to fourth legs. We show here that this phenotype correlates with the loss of Distal-less and concomitant expression of Antennapedia in the limb primordium. Unlike its Drosophila counterpart, Daphnia Antennapedia represses Distal-less in Drosophila assays...
Journal Articles
Journal: Development
Development (2002) 129 (8): 1967–1974.
Published: 15 April 2002
... for antenna development. The nuclear factors, Homothorax, Distal-less and Spineless, are each required for particular aspects of antennal fate. Coexpression of Homothorax, necessary for nuclear localization of its ubiquitously expressed partner Extradenticle, with Distal-less is required to establish antenna...
Journal Articles
Journal: Development
Development (2002) 129 (3): 695–704.
Published: 1 February 2002
... that bric a brac expression is activated early throughout most of the Distal-less domain in both antenna and leg and subsequently is restricted to the distal portion and into rings. Although bric a brac expression in the antenna and in all four tarsal rings of the leg requires Distal-less, only the proximal...
Journal Articles
Journal: Development
Development (2001) 128 (22): 4511–4521.
Published: 15 November 2001
... arise. I further demonstrate that the proximal-distal patterning genes homothorax and dachshund are positively required, while Distal-less is unexpectedly negatively required, to establish the segmental pattern of Notch ligand and fringe expression. Two Serrate enhancers that respond to regulation...
Journal Articles
Journal: Development
Development (2001) 128 (14): 2803–2814.
Published: 15 July 2001
... genetic studies have revealed a developmental system for patterning appendages and identified several genes required for limb development. Among these are: extradenticle ( exd ) , homothorax ( hth ) , dachshund ( dac ), Distal-less ( Dll ) and spalt ( sal ). These limb genes have not been well studied...
Journal Articles
Journal: Development
Development (2001) 128 (12): 2365–2372.
Published: 15 June 2001
..., R. (1935) Book Principles of Insect Morphology . New York: McGraw-Hill). To gain insight into how variations between the antenna and the leg may have arisen, we have compared the epistatic relationships among three major proximodistal patterning genes, Distal-less , dachshund and homothorax...