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Keywords: Discs largeClose
Development (2019) 146 (18): dev174763.
Published: 23 September 2019
...Zohreh Sharifkhodaei; Mary M. Gilbert; Vanessa J. Auld ABSTRACT Junctional complexes that mediate cell adhesion are key to epithelial integrity, cell division and permeability barrier formation. In Drosophila , the scaffolding proteins Scribble (Scrib) and Discs Large (Dlg) are key regulators...
Includes: Supplementary data
Development (2003) 130 (9): 1927–1935.
Published: 1 May 2003
... large . Clonal studies indicate that follicle cell Bazooka acts as a permissive factor during cell invasion,possibly by stabilizing adhesion between the invading somatic cells and their substratum, the germline cells. Genetic epistasis experiments demonstrate that bazooka acts downstream of discs large...
Development (1993) 119 (Supplement): 239–249.
Published: 1 December 1993
... proliferation. Mutations in the discs large (dig) gene cause neoplastic overgrowth of imaginal discs in the larva. The mutant dises show loss of septate junctions and of apical-basal cell polarity, and they also lose the ability to differentiate cuticular structures. The dig protein product (DlgA) is localized...