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Keywords: Developmental pluripotency
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Journal Articles
Incomplete reactivation of Oct4 -related genes in mouse embryos cloned from somatic nuclei
Available to PurchaseAlex Bortvin, Kevin Eggan, Helen Skaletsky, Hidenori Akutsu, Deborah L. Berry, Ryuzo Yanagimachi, David C. Page, Rudolf Jaenisch
Journal:
Development
Development (2003) 130 (8): 1673–1680.
Published: 15 April 2003
... an Oct4 gene, which plays an essential role in control of developmental pluripotency, develop to the blastocyst stage and also die after implantation, because they lack pluripotent embryonic cells. Based on this similarity, we posited that cloned embryos derived from differentiated cell nuclei fail...
