... segmentation Convolutional neural networks Mouse embryo Developmental biology Morphometrics National Institute of Dental and Craniofacial Research http://dx.doi.org/10.13039/100000072 R01-DE019638 Natural Sciences and Engineering Research Council of Canada http://dx.doi.org/10.13039...

... pregnancy. Zika virus (ZIKV) Birth defects Miscarriage Developmental biology Cell fate Epidemic Michigan State University http://dx.doi.org/10.13039/100007709 National Institute of General Medical Sciences http://dx.doi.org/10.13039/100000057 R35 GM131759...

...Scott F. Gilbert; Michael G. Hadfield ABSTRACT What can developmental biology contribute toward mitigating the consequences of anthropogenic assaults on the environment and climate change? In this Spotlight article, we advocate a developmental biology that takes seriously Lynn Margulis' claim...

... peripheral axons (magenta) during caudal fin development described in this study. * Present address: Developmental Biology and Stem Cell Program, University of California, San Francisco, CA 94143, USA. ‡ Author for correspondence ( [email protected] ) Handling Editor: Steve Wilson...

... enabled detailed investigations into the fates of cells. Combined with powerful new advances in genomics and single-cell transcriptomics, the field of developmental biology is able to describe the formation of the embryo like never before. In this Review, we discuss some of the different strategies...

... at large. Leading scientists from a range of disciplines, including developmental biology, physics, chemistry and computer science, covered a gamut of topics from the principles of cell and tissue organization, patterning and gene regulatory networks, to synthetic approaches for exploring evolutionary...

... recent technical advances could help overcome some of the challenges in the field. Developmental biology Cell cycle Stem cells Tissue-specific stem cells, also known as adult stem cells, reside in somatic adult tissues, where they contribute to tissue homeostasis and repair ( Li...

...Gašper Tkačik; Thomas Gregor ABSTRACT Half a century after Lewis Wolpert's seminal conceptual advance on how cellular fates distribute in space, we provide a brief historical perspective on how the concept of positional information emerged and influenced the field of developmental biology...

... . Developmental biology Pluripotency Totipotency Embryonic development proceeds from a single fertilized egg to generate all lineages that make up the future organism. In mammals, the initial rounds of cell division result in the expansion of a pool of equipotent cells (termed blastomeres...

... ). Developmental biology Differentiation circRNAs Noncoding RNAs Stem cells Summary: This Review summarizes the current knowledge of circRNAs, a complex family of eukaryotic transcripts with important biological features, and discusses the possible functions of circRNAs in cell differentiation...

...Martin Johnson ABSTRACT This article describes the origins and development of in vitro fertilisation (IVF) and how it was influenced by, and influenced, basic research in developmental biology. It describes the technical and social challenges that confronted the pioneers in this field of study...

... presented at the EMBO-EMBL Symposium ‘Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture’ held in Germany in March 2019. Cells Developmental biology Engineering Genetics Modeling Synthetic biology The Paul G. Allen Frontiers Group Barton Family Foundation...

... Sciences Research Council 10.13039/501100000268 BB/L023555/1 Multiscale modelling Vascular pattern Auxin Cytokinin Developmental biology Root biology Summary: A gene regulatory network that generates a diarch vascular pattern in Arabidopsis roots can produce the range of patterns...

... to understand the development of organs and organisms. Here, I present some of the latest modeling projects in the field, covering a wide range of developmental biology concepts, from molecular patterning to tissue morphogenesis. Rather than classifying them according to scientific question, or scale of problem...

... and reaction-diffusion, two fundamental principles governing the arisal of structures and shapes in organisms. Reaction-diffusion Biological pattern Developmental biology History of ideas The problem of patterning the embryo is almost synonymous with developmental biology itself. One can trace...