... pellucida, highlighting a potential risk of sexually transmitted infection in early pregnancy. Zika virus (ZIKV) Birth defects Miscarriage Developmental biology Cell fate Epidemic Michigan State University http://dx.doi.org/10.13039/100007709 National Institute of General...

...Scott F. Gilbert; Michael G. Hadfield ABSTRACT What can developmental biology contribute toward mitigating the consequences of anthropogenic assaults on the environment and climate change? In this Spotlight article, we advocate a developmental biology that takes seriously Lynn Margulis' claim...

... that the proximal neurovascular-bone relationship in the adult caudal fin is established during fin organogenesis and suggests that ray-associated osteoblasts pattern axons and endothelium. * Present address: Developmental Biology and Stem Cell Program, University of California, San Francisco, CA 94143, USA...

... enabled detailed investigations into the fates of cells. Combined with powerful new advances in genomics and single-cell transcriptomics, the field of developmental biology is able to describe the formation of the embryo like never before. In this Review, we discuss some of the different strategies...

... at large. Leading scientists from a range of disciplines, including developmental biology, physics, chemistry and computer science, covered a gamut of topics from the principles of cell and tissue organization, patterning and gene regulatory networks, to synthetic approaches for exploring evolutionary...

... and therefore contributing to the declining performance of tissues ( Goodell and Rando, 2015 ; Schultz and Sinclair, 2016 ; Tümpel and Rudolph, 2019 ). This decline in stem cell function is due to both intrinsic mechanisms and changes in extrinsic signals from the environment. Developmental biology...

...Gašper Tkačik; Thomas Gregor ABSTRACT Half a century after Lewis Wolpert's seminal conceptual advance on how cellular fates distribute in space, we provide a brief historical perspective on how the concept of positional information emerged and influenced the field of developmental biology...

... . Developmental biology Pluripotency Totipotency Embryonic development proceeds from a single fertilized egg to generate all lineages that make up the future organism. In mammals, the initial rounds of cell division result in the expansion of a pool of equipotent cells (termed blastomeres...

... differentiation and development. Developmental biology Differentiation circRNAs Noncoding RNAs Stem cells Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules that were identified many years ago but have only recently attracted the attention of the general scientific...

...Martin Johnson ABSTRACT This article describes the origins and development of in vitro fertilisation (IVF) and how it was influenced by, and influenced, basic research in developmental biology. It describes the technical and social challenges that confronted the pioneers in this field of study...

... presented at the EMBO-EMBL Symposium ‘Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture’ held in Germany in March 2019. Cells Developmental biology Engineering Genetics Modeling Synthetic biology Understanding the basic principles by which complex organisms self-assemble...

... modelling Vascular pattern Auxin Cytokinin Developmental biology Root biology Patterning of organs involves the organization of cell fates within a tissue in space and time. Although the molecular networks that control pattern formation may be considered as deterministic, there is increasing...

... to understand the development of organs and organisms. Here, I present some of the latest modeling projects in the field, covering a wide range of developmental biology concepts, from molecular patterning to tissue morphogenesis. Rather than classifying them according to scientific question, or scale of problem...

... and reaction-diffusion, two fundamental principles governing the arisal of structures and shapes in organisms. Reaction-diffusion Biological pattern Developmental biology History of ideas The problem of patterning the embryo is almost synonymous with developmental biology itself. One can trace...