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Keywords: Development
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Journal Articles
Journal: Development
Development (2022) 149 (10): dev200446.
Published: 16 May 2022
... signaling did not alter the number of Six2 + progenitors ( Fig. 5 D). Whereas physiological Notch signals are not acting to switch cells from self-renewal to differentiation, Notch signals could promote proximal development within a developmental window, defined pharmacologically with γ-secretase...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (8): dev200270.
Published: 3 May 2022
... with traditional models. Finally, iPSC-derived organoid systems have also become increasingly popular as a tool to study human development and organogenesis, but many of them are lacking in the developmental cues provided by RTMs and, as such, might not be fully representative. It would be interesting to see...
Journal Articles
Journal: Development
Development (2022) 149 (6): dev200243.
Published: 23 March 2022
..., are enlarged and accumulate massively at the last larval and white prepupal stage ( Rusten et al., 2004 ; Butterworth et al., 1988 ; Butterworth and Forrest, 1984 ). The steroid hormone ecdysone, the master regulator of insect development, drives developmental autophagy in the fat body through downregulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (5): dev200028.
Published: 28 February 2022
... stepwise developmental changes in their cell cycle and metabolic properties. Genetic studies further show that cross-repression contributes to the mutually exclusive expression of Olig2 and Gsx2 in NSCs/progenitors during embryogenesis, but that their expression is regulated independently from each other...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (2): dev200118.
Published: 20 January 2022
... serving as a template of stable cell identity ( Mayran et al., 2018 ; Reizel et al., 2021 ). The process of cell fate determination during development is largely directed by local morphogens, which serve as developmental signals to transduce programmed changes in methylation into stable patterns...
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200059.
Published: 15 December 2021
....2013.08.012 George , S. H. L. , Gertsenstein , M. , Vintersten , K. , Korets-Smith , E. , Murphy , J. , Stevens , M. E. , Haigh , J. J. and Nagy , A. ( 2007 ). Developmental and adult phenotyping directly from mutant embryonic stem cells . Proc. Natl. Acad. Sci. USA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200030.
Published: 7 December 2021
... in multiple embryonic tissues. Hif1a −/− embryos are grossly abnormal, displaying a variety of developmental defects, including poor angiogenesis, failure of neural tube closure, branchial arch hypoplasia, pericardial effusion, brain tissue deficiency and cardiac hyperplasia. Hif1a −/− embryos suffer...
Journal Articles
Journal: Development
Development (2021) 148 (20): dev199731.
Published: 14 October 2021
..., Princeton University, NJ, USA) and anti-Fmi #74 (1:20, developed by T. Uemura) were obtained from the Developmental Studies Hybridoma Bank. Secondary antibodies used were rhodamine red-X donkey anti-rabbit, anti-rat and anti-mouse, fluorescein isothiocyanate (FITC) donkey anti-rabbit, anti-rat and anti...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (11): dev199609.
Published: 12 June 2021
... in Development and Disease’, organized by Irene Miguel-Aliaga, Ralph DeBerardinis and Marian Walhout, it became clear that the field of developmental and disease metabolism is maturing and moving on. Over the course of these 2 days, the work of Warburg, and the important influence it long had on this budding...
Journal Articles
Journal: Development
Development (2021) 148 (11): dev199409.
Published: 28 May 2021
... developmental functions, accumulating evidence points towards the heterogeneity of this neuronal population in terms of molecular profile, ontogenetic origins, migration routes and cell death fate. The recent development of single cell technologies now enables us to understand what is common and what...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (10): dev196147.
Published: 27 May 2021
... to cover developmental stages starting immediately before neural tube formation until the peak of neurogenesis in the cerebral cortex ( Martynoga et al., 2012 ; Chen et al., 2017 ). Overall, our study highlights the importance of Brg1 for brain and eye development as well as its time-specific role...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (10): dev180794.
Published: 17 May 2021
... , M. , Casey , J. , Belus , M. T. , Fedder , K. N. , Dahal , G. R. and Bates , E. A. ( 2019 ). Ion channel contributions to wing development in Drosophila melanogaster . G3 9 , 999 - 1008 . 10.1534/g3.119.400028 Gilbert , S. ( 2000 ). Developmental...
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (9): dev199418.
Published: 7 May 2021
...Robin M. Perelli; Matthew L. O'Sullivan; Samantha Zarnick; Jeremy N. Kay ABSTRACT Angiogenesis in the developing mammalian retina requires patterning cues from astrocytes. Developmental disorders of retinal vasculature, such as retinopathy of prematurity (ROP), involve arrest or mispatterning...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev198507.
Published: 29 April 2021
... in Excel. We thank the Bloomington Drosophila Stock Center (Indiana University), the Drosophila Genetic Resource Center (Indiana University), and the Kyoto Stock Center (Kyoto Institute of Technology) for fly stocks, and the Developmental Studies Hybridoma Bank (University of Iowa) for antibodies...
Journal Articles
Journal: Development
Development (2021) 148 (18): dev192773.
Published: 12 March 2021
... between two cells is determined by the pressure difference between these cells; all pressure differences between cells can also be determined by the same logic. Stress inference is a very promising approach to link mechanics and developmental processes, from the cellular to the tissue scale...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (5): dev188490.
Published: 12 March 2021
.... , Gittenberger-de Groot , A. C. , Sariola , H. , Friedman , R. , Boivin , G. P. , Cardell , E. L. and Doetschman , T. ( 1997 ). TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes . Development 124 , 2659...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (1): dev182741.
Published: 13 January 2021
... in cytoplasmic lncRNAs that have defined molecular mechanisms linked to cellular or developmental functions are as yet under-represented. One of the most studied interaction partners of cytoplasmic lncRNAs are miRNAs, which are small RNAs of ∼22 nt that regulate virtually every aspect of development and normal...
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194498.
Published: 23 December 2020
... dynamic expression during embryogenesis ( Burguera et al., 2017 ; Bebee et al., 2015 ). The developmental importance of Esrp1/2 is underscored by their conservation across species, from ascidians to zebrafish, Xenopus , mouse and humans ( Burguera et al., 2017 ). Gene variant in ESRP2 was also...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev190173.
Published: 30 November 2020
... in A-F; 5 μm in A′-F′; 1 μm in G-J; 10 μm in K,L. Fig. 6. The Zfp423 mutant ChP fails to develop a multiciliated epithelium. (A-F′) Parasagittal cerebellar sections of the hChP were obtained at different developmental stages and stained for Arl13b and γ-tubulin, to visualize cilia and basal bodies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev193714.
Published: 19 November 2020
... embryonic developmental pathways has remained enigmatic. We have standardized and established a sponge Sycon ciliatum regeneration protocol from dissociated cells. Morphological analysis demonstrated that dissociated sponge cells follow a series of morphological events resembling postembryonic development...
Includes: Supplementary data