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Keywords: Development
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Journal Articles
Journal: Development
Development (2021) 148 (9): dev199418.
Published: 07 May 2021
...Robin M. Perelli; Matthew L. O'Sullivan; Samantha Zarnick; Jeremy N. Kay ABSTRACT Angiogenesis in the developing mammalian retina requires patterning cues from astrocytes. Developmental disorders of retinal vasculature, such as retinopathy of prematurity (ROP), involve arrest or mispatterning of...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (5): dev188490.
Published: 12 March 2021
.... , Sariola , H. , Friedman , R. , Boivin , G. P. , Cardell , E. L. and Doetschman , T. ( 1997 ). TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes . Development 124 , 2659 - 2670 . Schier , A. F...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev192773.
Published: 12 March 2021
... ) version: the ‘tissue stress'. Stress inference is a very promising approach to link mechanics and developmental processes, from the cellular to the tissue scale. In this Primer, we provide a beginner's guide to stress inference; our goal is to make the approach more accessible to the scientific...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (1): dev182741.
Published: 13 January 2021
...Florian Constanty; Alena Shkumatava ABSTRACT The number of long noncoding RNAs (lncRNAs) with characterized developmental and cellular functions continues to increase, but our understanding of the molecular mechanisms underlying lncRNA functions, and how they are dictated by RNA sequences, remains...
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194498.
Published: 23 December 2020
... ). Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas . Proc. Natl. Acad. Sci. USA   108 , 13710 - 13715 . 10.1073/pnas.1110931108 Burguera , D. , Marquez , Y. , Racioppi , C. , Permanyer , J. , Torres-Mendez , A. , Esposito , R. , Albuixech...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev190173.
Published: 30 November 2020
... Wurst , W. , Rossant , J. , Prideaux , V. , Kownacka , M. , Joyner , A. , Hill , D. P. , Guillemot , F. , Gasca , S. , Cado , D. , Auerbach , A. , et al. ( 1995 ). A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev193714.
Published: 19 November 2020
... embryonic developmental pathways has remained enigmatic. We have standardized and established a sponge Sycon ciliatum regeneration protocol from dissociated cells. Morphological analysis demonstrated that dissociated sponge cells follow a series of morphological events resembling postembryonic development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev194100.
Published: 15 November 2020
...Pooja Flora; Elena Ezhkova ABSTRACT Cell divisions and cell-fate decisions require stringent regulation for proper tissue development and homeostasis. The mammalian epidermis is a highly organized tissue structure that is sustained by epidermal stem cells (ESCs) that balance self-renewal and cell...
Journal Articles
Journal: Development
Development (2020) 147 (19): dev161430.
Published: 05 October 2020
...Albert Tsai; Rafael Galupa; Justin Crocker ABSTRACT Developmental enhancers drive gene expression in specific cell types during animal development. They integrate signals from many different sources mediated through the binding of transcription factors, producing specific responses in gene...
Journal Articles
Journal: Development
Development (2020) 147 (18): dev189738.
Published: 28 September 2020
... of Dennis O'Leary, Henry Kennedy and others, explored this question using retrograde tracers. They found that the adult and developing L5 contains both CPNs and subcerebral projecting neurons (SCPNs). Importantly, the two subpopulations were clearly segregated at all developmental stages ( Stanfield...
Journal Articles
Journal: Development
Development (2020) 147 (15): dev182675.
Published: 03 August 2020
... developmental milestones and ISC specification are tightly regulated by signalling pathways and tissue-specific transcriptional control. For example, it is well characterised that the gut-specific transcription factor caudal type homeobox 2 (Cdx2) is required for the normal development of the primitive gut, as...
Journal Articles
Journal: Development
Development (2020) 147 (12): dev175059.
Published: 19 June 2020
... ). Evolutionary crossroads in developmental biology: amphioxus . Development   138 , 4819 - 4830 . 10.1242/dev.066720 Bickley , S. R. B. and Logan , M. P. O. ( 2014 ). Regulatory modulation of the T-box gene Tbx5 links development, evolution, and adaptation of the sternum . Proc. Natl. Acad...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (7): dev184507.
Published: 06 April 2020
..., and exhibit reduced grip strength, muscle weakness and increased interstitial fibrosis ( Acakpo-Satchivi et al., 1997 ). In addition, two developmental isoforms, MyHC-embryonic (encoded by Myh3 ) and MyHC-perinatal (encoded by Myh8 ), are expressed during embryonic, fetal and neonatal development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (5): dev184564.
Published: 02 March 2020
.... Methods   9 , 357 - 359 . 10.1038/nmeth.1923 Lawrence , P. A. , Struhl , G. and Morata , G. ( 1979 ). Bristle patterns and compartment boundaries in the tarsi of Drosophila . J. Embryol. Exp. Morphol.   51 , 195 - 208 . Lewis , E. B. ( 1963 ). Genes and developmental...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (2): dev180646.
Published: 17 January 2020
...Abigail K. Myers; Jessica G. Cunningham; Skye E. Smith; John P. Snow; Catherine A. Smoot; Eric S. Tucker ABSTRACT The precise migration of cortical interneurons is essential for the formation and function of cortical circuits, and disruptions to this key developmental process are implicated in the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (22): dev163428.
Published: 27 November 2019
... transcriptional regulation . Hum. Reprod.   31 , 1300 - 1314 . 10.1093/humrep/dew077 Georgiades , P. , Ferguson-Smith , A. C. and Burton , G. J. ( 2002 ). Comparative developmental anatomy of the murine and human definitive placentae . Placenta   23 , 3 - 19 . 10.1053/plac.2001.0738...
Journal Articles
Journal: Development
Development (2019) 146 (20): dev179309.
Published: 18 October 2019
..., the range of pattern transformations possible in animal development. In this work we use one such model, EmbryoMaker ( Marin-Riera et al., 2015 ), to simulate many possible developmental mechanisms and try to discover what, if anything, the mechanisms leading to robust complex morphologies have in...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2019) 146 (20): dev174409.
Published: 17 October 2019
... integrating existing knowledge of the molecular and genetic machinery underlying retinal development is crucial not only for elucidating normal developmental mechanisms but also for developing therapeutic interventions aimed at vision restoration ( Bassett and Wallace, 2012 ). Determining the mechanism of OC...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (20): dev180349.
Published: 01 October 2019
... systems of human embryos and fetuses. The aim of that effort is to build an atlas of human development comprising 3D images at an unprecedented cellular resolution that are based on the direct imaging of whole-mount tissues, rather than on 3D reconstructions of sections, and can be used by developmental...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (19): dev179523.
Published: 30 September 2019
... configurations, the expression pattern of Shh during embryonic development appears to be normal and mRNA levels are largely unchanged, with the resulting mice having no detectable phenotype. This indicates that communication between Shh and its extensive set of developmental enhancers is remarkably robust to...
Includes: Supplementary data