... that kinesin-1 heavy chain Kif5b plays important roles in anterograde transport of α-sarcomeric actin, non-muscle myosin IIB, together with intermediate filament proteins desmin and nestin to the growing tips of the elongating myotubes. Mice with Kif5b conditionally knocked out in myogenic cells showed...

...-express Alx4 (arrowheads in A′,A′), and the superficial Dermo1 + domain of the dermis (arrowheads in C′,C′). Control labeled cells also home to the myotome, where most co-express Pax7 (arrowheads in E′) and some are desmin + (arrowheads in G′). GFP + cells are also Pax7 + in the intermediate...

... directional cell migration and fiber formation, and their effects were mediated through RhoA. Although myoblast specification was not affected, expression of the intermediate filament desmin was reduced. Hence, Slit1 and Robo2, via RhoA, act to pattern formation of the pioneer myotome through the regulation...

... mechanisms underlie the establishment of pioneer and later myotomal waves. * Author for correspondence (e-mail: [email protected] ) 18 1 2006 © 2006. 2006 Adherens junctions Asymmetric cell division Avian embryo Cell adhesion Dermis Dermomyotome Desmin...

... is a marker for DM-derived mitotic cells in the myotome and that it disappears from the forming dermis( Fig. 2D ), enabled us to follow the relative onset of these two cell types. At flank regions of the axis, the epithelial DM of stage 18 embryos expressed PAX7 but the underlying desmin-immunoreactive...

... fixed in 4% formaldehyde, processed for paraffin wax embedding, sectioned at 10μm, and immunolabeled with anti GFP( Burstyn-Cohen and Kalcheim,2002 ) and desmin antibodies. Laser-scanning confocal microscopy and digital imaging were performed as already described ( Cinnamon et al.,2001 ). Frozen...

...-suff.cc.huji.ac.il ) 5 3 2002 © 2002. 2002 Avian embryo Cell delamination Desmin Dermomyotome Epithelial-mesenchymal conversion Myoblast migration Pioneer myoblasts Somite In the early embryo, muscle progenitor cells arising in the somites differentiate into myofibers that give rise...

... for correspondence (e-mail: [email protected] ) © 1997 by Company of Biologists 1997 cartilage desmin extracellular matrix gelatinase matrix metalloproteinase tongue TIMP collagenase stromelysin bone Matrix metalloproteinases (MMPs) have been implicated in pathological and invasive...

... then differentiated in ovo in dermis, cartilage and skeletal muscle as they normally do in the course of development and were able to migrate into chick host limb. To trace the behavior of somitic myogenic stem cells more closely, somites arising from mice bearing a transgene of the desmin gene linked to a reporter...

...G. Schaart; C. Viebahn; W. Langmann; F. Ramaekers ABSTRACT The expression of the intermediate filament (IF) constituents desmin, vimentin and keratin, as well as the striated-muscle-specific marker titin, was studied in mouse embryos of 8.0 to 9.5 days post coitum (d.p.c.), using the indirect...

...Harald Herrmann; Bernadette Fouquet; Werner W. Franke ABSTRACT During embryogenesis of avian and mammalian species the formation of intermediate filaments (IFs) containing desmin is characteristic for myogenesis. In view of important differences of patterns of IF protein expression in embryogenic...