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Keywords: Derepression
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Journal Articles
Journal: Development
Development (2004) 131 (16): 4071–4083.
Published: 15 August 2004
...-Pbx-Prep ternary complex formation and regulation of the Phox2b enhancer activity in ventral r4. Moreover, the DV factor Nkx2.2 enhances Hox-mediated transactivation via a derepression mechanism. Finally, we show that induction of ectopic Phox2b -expressing visceral motoneurons in the chick hindbrain...
Journal Articles
Journal: Development
Development (2004) 131 (14): 3295–3306.
Published: 15 July 2004
... motoneurons. These findings provide direct support for the derepression model of gene regulation and cell fate specification in the neural tube, as well as establishing a role for enhancers in targeting gene expression to a single neuronal subtype in the spinal cord. To determine whether additional...
Includes: Supplementary data