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Keywords: Default model
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Journal Articles
Journal: Development
Development (2004) 131 (22): 5671–5681.
Published: 15 November 2004
...Claudia Linker; Claudio D. Stern A dominant molecular explanation for neural induction is the `default model', which proposes that the ectoderm is pre-programmed towards a neural fate, but is normally inhibited by endogenous BMPs. Although there is strong evidence favouring this in Xenopus , data...
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (10): 2071–2081.
Published: 15 May 2003
..., Chordin and Follistatin,which are secreted from the organizer region that differentiates into axial mesoderm. Initially, neural-inducing signals from the organizer are thought to act in an instructive manner. They can, however, also bind directly to BMP proteins. This leads to the `default model...