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Keywords: Dauer formation
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Journal Articles
Journal: Development
Development (2014) 141 (8): 1767–1779.
Published: 15 April 2014
...Wesley L. Hung; Ying Wang; Jyothsna Chitturi; Mei Zhen Adverse environmental conditions trigger C. elegans larvae to activate an alternative developmental program, termed dauer diapause, which renders them stress resistant. High-level insulin signaling prevents constitutive dauer formation. However...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2010) 137 (20): 3501–3511.
Published: 15 October 2010
... larva at the end of the second larval stage. Here, we show that the period homolog lin-42 , known to control developmental time, also acts as a component of a switch that mediates dauer entry. Loss of lin-42 function renders animals hypersensitive to dauer formation under stressful conditions, whereas...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (3): 477–485.
Published: 1 February 2010
... Smad in vivo and in vitro. Overexpression of daf-8 conferred a dauer-defective phenotype and suppressed constitutive dauer formation in daf-8 and daf-14 mutants. In contrast to mammalian systems described thus far, active DAF-3 drives a feedback regulatory loop that represses transcription of daf-7...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (5): 867–879.
Published: 1 March 2007
... in vivo provide further evidence for the recently proposed pump-independent scaffolding functions of P-type ATPases in the modulation of intracellular signaling. P-type ATPase Developmental timing Dauer formation DAF-2/InsR Ras-MAPK Caenorhabditis elegans During embryonic...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (1): 221–231.
Published: 1 January 2002
...) lon-2(e678) + . *Author for correspondence (e-mail: [email protected] ) 11 10 2001 © 2002. 2002 Cytochrome P450 Dauer formation Aging daf-9 daf-12 TGF-β Insulin C. elegans is a useful model for defining the signaling pathways that transduce...