1-12 of 12
Keywords: Dauer
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2020) 147 (20): dev190082.
Published: 27 October 2020
...Agnieszka Podraza-Farhanieh; Balasubramanian Natarajan; Dorota Raj; Gautam Kao; Peter Naredi ABSTRACT Insulin/IGF signaling in Caenorhabditis elegans is crucial for proper development of the dauer larva and growth control. Mutants disturbing insulin processing, secretion and downstream signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1273–1282.
Published: 01 April 2017
...Colin E. Delaney; Albert T. Chen; Jacqueline V. Graniel; Kathleen J. Dumas; Patrick J. Hu Animals change developmental fates in response to external cues. In the nematode Caenorhabditis elegans , unfavorable environmental conditions induce a state of diapause known as dauer by inhibiting the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (12): 2177–2186.
Published: 15 June 2012
... conditions, developing larvae enter a stress-resistant, quiescent stage called ‘dauer’. Dauer larvae are characterized by the arrest of all progenitor cell lineages at a stage equivalent to the end of the second larval stage (L2). If dauer larvae encounter conditions favorable for resumption of reproductive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (4): 671–680.
Published: 15 February 2010
... the basis for the fertility defect had not been previously characterized. We found that IIR signaling is required for robust larval germline proliferation, separate from its well-characterized role in preventing dauer entry. IIR signaling stimulates the larval germline cell cycle. This activity is...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2583–2592.
Published: 01 August 2008
... neuronal function in postmitotic,differentiated neurons. Here, we demonstrate a novel role for the canonical Notch signalling pathway in postmitotic neurons during a specialised`diapause-like' post-embryonic developmental stage in C. elegans called dauer. Our data suggest that cell signalling downstream of...
Journal Articles
Journal: Development
Development (2008) 135 (13): 2239–2249.
Published: 01 July 2008
...Dhaval S. Patel; Lily L. Fang; Danika K. Svy; Gary Ruvkun; Weiqing Li In C. elegans , steroid hormones function in conjunction with insulin/IGF-1-like signaling in promoting reproductive development over entry into the diapausal dauer stage. The NCR-1 and -2 (NPC1-related) intracellular cholesterol...
Journal Articles
Journal: Development
Development (2006) 133 (4): 611–619.
Published: 15 February 2006
... cycle quiescence in the germline stem cell population, in addition to prolonging lifespan. The inactivation of either protein causes aberrant germline proliferation during diapause-like `dauer' development, whereas the loss of AMPK uncouples developmental arrest from lifespan extension. Reduced TGF-β...
Journal Articles
Journal: Development
Development (2004) 131 (22): 5741–5752.
Published: 15 November 2004
... exact function remains unclear. The C. elegans genome contains two homologs of NPC1, ncr-1 and ncr-2 , and an ncr-2;ncr-1 double deletion mutant forms dauer larvae constitutively (Daf-c). We have analyzed the phenotypes of ncr single and double mutants in detail, and determined the ncr gene expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (8): 1765–1776.
Published: 15 April 2004
...Birgit Gerisch; Adam Antebi In response to the environment, the nematode C. elegans must choose between arrest at a long-lived alternate third larval stage, the dauer diapause, or reproductive development. This decision may ultimately be mediated by daf-9 , a cytochrome P450 related to...
Journal Articles
Journal: Development
Development (2004) 131 (8): 1777–1786.
Published: 15 April 2004
...Ho Yi Mak; Gary Ruvkun Parallel pathways control C. elegans reproductive development in response to environmental cues. Attenuation of daf-2 insulin-like or daf-7 TGFβ-like signaling pathways cause developmental arrest at the stress resistant and long-lived dauer stage. Loss-of-function mutations...
Journal Articles
Journal: Development
Development (2004) 131 (2): 435–446.
Published: 15 January 2004
...Li S. da Graca; Karen K. Zimmerman; Melissa C. Mitchell; Marianne Kozhan-Gorodetska; Kamila Sekiewicz; Yairani Morales; Garth I. Patterson,, An unconventional TGFβ superfamily pathway plays a crucial role in the decision between dauer diapause and reproductive growth. We have studied the daf-5 gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (8): 1621–1634.
Published: 15 April 2003
...John Wang; Stuart K. Kim The dauer is a developmental stage in C. elegans that exhibits increased longevity, stress resistance, nictation and altered metabolism compared with normal worms. We have used DNA microarrays to profile gene expression differences during the transition from the dauer state...
Includes: Supplementary data