... networks, which include the distal-less (Dlx) gene family. However, the functional significance of Dlx5 in patterning the oropharyngeal region has remained unknown. Here, we show that loss of Dlx5 leads to a shortened soft palate and an absence of the levator veli palatini, palatopharyngeus...

... osteogenesis imperfecta . Am. J. Hum. Genet.   87 , 110 - 114 . 10.1016/j.ajhg.2010.05.016 Lee , M.-H. , Kwon , T.-G. , Park , H.-S. , Wozney , J. M. and Ryoo , H.-M. ( 2003 ). BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2 . Biochem. Biophys...

.... Here, we show that ectethmoid formation depends upon Dlx5 and Dlx6 expression in a restricted ectodermal territory of the anterior neural folds, which we name NF-ZA. In both chick and mouse neurulas, Dlx5 and Dlx6 expression is mostly restricted to NF-ZA. Simultaneous Dlx5 and Dlx6 inactivation...

... the onset of fusion, but how the O-N pattern is established and how it relates to the expansion and fusion of the palatal shelves are unknown. Here we address these questions and show that O-N patterning is associated with the expansion and fusion of the palatal shelves and that Dlx5 is required for the O-N...

... Acampora, D., Merlo, G. R., Paleari, L., Zerega, B.,Postiglione, M. P., Mantero, S., Bober, E., Barbieri, O., Simeone, A. and Levi, G. ( 1999 ). Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development 126 , 3795 -3809. Attisano, L., Carcamo, J...

... of the region where lineage-specific markers such as Mash1 and Ngn1 are expressed ( Fig. 1 ). The Fgf8 mRNA expression domain expands and comes to include neuroepithelial cells that express genes that are definitive markers of olfactory neuroepithelium, including Sox2, Dlx5 and Pax6 ( Fig. 1 and see...

... (10-50 pg)( Dale et al., 1992 ), eya1 (400 pg) ( David et al.,2001 ), zic2 (100 pg)( Brewster et al., 1998 ), foxD3 (25 pg) ( Sasai et al.,2001 ) (from D. Kessler), dlx5 (200 pg)( Luo et al., 2001a ), dlx6 (200 pg) ( Luo et al.,2001a ) and sox2 (200 pg)( Mizuseki et al., 1998 ) (from T...

... 2002. 2002 Emx1 Dlx2 En1 Dlx5 Neurosphere Mouse Cell fate The vertebrate brain is divided into specialized regions during development. A prevailing model proposes that regional specialization in the vertebrate brain is broadly established through the formation of transient...