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Keywords: DAF-16
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Journal Articles
Journal Articles
Journal: Development
Development (2011) 138 (10): 2059–2068.
Published: 15 May 2011
... in X:A signal assessment. We also show that sea-2 modulates aging in adulthood. Loss of function of sea-2 slows the aging process and extends the adult lifespan in a DAF-16/FOXO-dependent manner. Mutation of sea-2 promotes nuclear translocation of DAF-16 and subsequent activation of daf-16 targets. We...
Includes: Supplementary data