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Keywords: Cytoplasmic invagination
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Journal Articles

CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility

Open Access
Keisuke Shimada, Masahito Ikawa
Journal: Development
Development (2023) 150 (21): dev201724.
https://doi.org/10.1242/dev.201724
Published: 30 October 2023
... causes male infertility with morphological and motility defects in spermatozoa. Owing to the lack of CCDC183, centrioles after elongation of axonemal microtubules do not connect the cell surface and nucleus during spermiogenesis, which causes subsequent loss of cytoplasmic invagination around...
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Includes: Supplementary data