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Development (2012) 139 (11): 1921–1930.
Published: 01 June 2012
... injured heart. TGFβ ligands are locally induced following cryoinjury and activate the signaling pathway both in the infarct area and in cardiomyocytes in the vicinity of the trauma zone. Inhibition of the relevant type I receptors with the specific chemical inhibitor SB431542 qualitatively altered the...
Includes: Supplementary data
Development (2011) 138 (9): 1663–1674.
Published: 01 May 2011
... removal of heart tissue rather than its damage. Here, we characterize the cellular response and regenerative capacity of the zebrafish heart after cryoinjury, an alternative procedure that more closely models the pathophysiological process undergone by the human heart after myocardial infarction (MI...
Includes: Multimedia, Supplementary data