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Keywords: Crescent
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Journal Articles
Journal: Development
Development (2009) 136 (24): 4083–4088.
Published: 15 December 2009
... and Crescent (Cres), which are members of the sFRP family, have the ability to regulate the diffusibility and signalling areas of the Wnt ligands Wnt8 and Wnt11. We found, using the Xenopus embryo, that Wnts do not diffuse effectively, whereas Frzb and Cres spread very widely. Interestingly, Frzb and Cres...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (7): 1071–1081.
Published: 1 April 2009
.... In an unbiased microarray screen, we defined genes encoding the sFRPs Frzb-1 and Crescent as transiently and locally expressed in the primary mouth anlage. Using antisense oligonucleotides and `face transplants', we show that frzb-1 and crescent expression is specifically required in the primary mouth region...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (15): 2915–2927.
Published: 1 August 2001
..., misexpression of Wnt1 in the area pellucida enables this region to form a primitive streak in response to cVg1. Third, the Wnt antagonists Crescent and Dkk-1 block the primitive streak-inducing ability of cVg1 in the marginal zone. These findings suggest that Wnt activity defines the marginal zone and allows...