.... , Zürn , C. , Schamel , W. W. A. and Reth , M. ( 1999 ). Comparison of the tamoxifen regulated chimeric Cre recombinases MerCreMer and CreMer . Biol. Chem.   380 , 1435 - 1438 . 10.1515/BC.1999.184 Warchol , M. E. , Massoodnia , R. , Pujol , R. , Cox , B. C...

... ( http://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Clonal lineage CRE recombinase piggyBac transposase Multi-fluorescence Progenitor cells Fate mapping...

..., TN 37232-0225, USA 8 11 2006 © 2007. 2007 Notch Regulated intramembrane proteolysis (RIP) Cre recombinase Fate mapping Stem cells Mouse Notch signaling controls spatial patterning and cell fate decisions throughout the animal kingdom( Artavanis-Tsakonas et al.,1999...

..., IN 46285, USA 23 9 2005 ©2005. 2005 FGF Vomeronasal organ Neurogenesis Olfactory epithelium Nasal cavity Stem cell Apoptosis Cre recombinase Fgf8 Foxg1 Sox2 Pax6 Mash1 Neurogenin 1 Ncam1 Pyst1 Shh Dlx5 Neuronal progenitor Mouse mutant...

... equally to this work 17 6 2005 ©2005. 2005 Cre recombinase Fgf8 Kidney Lim1 Nephron Somitogenesis T-Cre Wnt4 Mouse Fibroblast growth factors (FGFs) play a role in numerous key developmental events, such as gastrulation and organogenesis including somite, brain...

... depends on DM cells in a non-cell-autonomous fashion. * Author for correspondence (e-mail: emonuki@uci.edu ) 23 5 2005 ©2005. 2005 Roof plate Fate map Genetic ablation Bmp Gdf7 Transgenic mice Cre recombinase Diphtheria toxin Mouse The choroid plexus (CP) produces...

...@lmls.med.kyoto-u.ac.jp ) * PRESTO, Japan Science and Technology Corporation (JST) 30 6 2003 © 2003. 2003 Mouse Cell lineage Cre recombinase It is well known that the future embryonic body axes are specified prior to the first cleavage in a variety of animals. In the case...

... in skeletal development. Embryos harboring homozygous null mutations in FGFR2 die prior to skeletogenesis. To address the role of FGFR2 in normal bone development, a conditional gene deletion approach was adopted. Homologous introduction of cre recombinase into the Dermo1 ( Twist2 ) gene locus resulted...

... and nulliparous females. *Authors for correspondence (e-mail: kuwagner@unmc.edu and gs4d@nih.gov ) 18 12 2001 © 2002. 2002 Mammary gland Cre recombinase Epithelium Parity Stem cells Involution Differentiation Mouse In mammals, steroid and peptide hormones in synergy...

... produced by odd-numbered rhombomeres. † Author for correspondence (e-mail: charnay@wotan.ens.fr ) 26 9 2001 © 2001. 2001 Segmentation Hindbrain Rhombomere Krox20 Cre recombinase Fate mapping Mouse The establishment of functional diversity in the vertebrate central...

... by expressing the Cre recombinase gene under control of the MMTV-LTR. By the age of five weeks, Bcl-x conditional mutant mice exhibited hyperproliferation of megakaryocytes and a decline in the number of circulating platelets. Three-month-old animals suffered from severe hemolytic anemia, hyperplasia...

...@mail.med.upenn.edu ) 18 02 1999 06 04 1999 © 2000 by Company of Biologists 2000 Pax3 Cardiogenesis connexin 43 Cre recombinase Neural crest Mouse In birds and mammals the complex process of cardiac morphogenesis requires interactions between multiple cell types intrinsic...

.... Determination of the fate of mammalian neural crest has been inhibited by the lack of appropriate markers. Here, we make use of a two-component genetic system for indelibly marking the progeny of the cranial neural crest during tooth and mandible development. In the first mouse line, Cre recombinase...

... of Biologists 2000 Neural crest Fate Mammal Cardiac development Cre recombinase Outflow tract In all vertebrate embryos, the heart initially forms as a single linear tube located along the ventral midline. Blood flow from the early heart is carried from the primordial ventricle through...